Mitochondrial dysfunctions induce PANoptosis and ferroptosis in cerebral ischemia/reperfusion injury: from pathology to therapeutic potential
R She, D Liu, J Liao, G Wang, J Ge… - Frontiers in Cellular …, 2023 - frontiersin.org
Ischemic stroke (IS) accounts for more than 80% of the total stroke, which represents the
leading cause of mortality and disability worldwide. Cerebral ischemia/reperfusion injury …
leading cause of mortality and disability worldwide. Cerebral ischemia/reperfusion injury …
The role of the antioxidant response in mitochondrial dysfunction in degenerative diseases: Cross‐talk between antioxidant defense, autophagy, and apoptosis
MLH Huang, S Chiang, DS Kalinowski… - Oxidative Medicine …, 2019 - Wiley Online Library
The mitochondrion is an essential organelle important for the generation of ATP for cellular
function. This is especially critical for cells with high energy demands, such as neurons for …
function. This is especially critical for cells with high energy demands, such as neurons for …
[HTML][HTML] Counteracting role of nuclear factor erythroid 2-related factor 2 pathway in Alzheimer's disease
A salient pathological features in Alzheimer's disease includes redox impairment and
neuroinflammation. Nuclear factor erythroid 2-related factor 2 (Nrf2) and Nuclear factor …
neuroinflammation. Nuclear factor erythroid 2-related factor 2 (Nrf2) and Nuclear factor …
Sphingolipids as a culprit of mitochondrial dysfunction in insulin resistance and type 2 diabetes
K Roszczyc-Owsiejczuk, P Zabielski - Frontiers in endocrinology, 2021 - frontiersin.org
Insulin resistance is defined as a complex pathological condition of abnormal cellular and
metabolic response to insulin. Obesity and consumption of high-fat diet lead to ectopic …
metabolic response to insulin. Obesity and consumption of high-fat diet lead to ectopic …
Dimethyl sulfoxide damages mitochondrial integrity and membrane potential in cultured astrocytes
C Yuan, J Gao, J Guo, L Bai, C Marshall, Z Cai… - PloS one, 2014 - journals.plos.org
Dimethyl sulfoxide (DMSO) is a polar organic solvent that is used to dissolve neuroprotective
or neurotoxic agents in neuroscience research. However, DMSO itself also has …
or neurotoxic agents in neuroscience research. However, DMSO itself also has …
Adverse effect of superoxide-induced mitochondrial damage in granulosa cells on follicular development in mouse ovaries
SAM Hoque, T Umehara, T Kawai… - Free radical biology and …, 2021 - Elsevier
High mitochondrial oxidative phosphorylation (mt-OXPHOS) levels are required to supply
the ATP necessary for follicle-stimulating hormone (FSH)-induced granulosa cell …
the ATP necessary for follicle-stimulating hormone (FSH)-induced granulosa cell …
Viruses as modulators of mitochondrial functions
Mitochondria are multifunctional organelles with diverse roles including energy production
and distribution, apoptosis, eliciting host immune response, and causing diseases and …
and distribution, apoptosis, eliciting host immune response, and causing diseases and …
Nano-Pulse Stimulation is a physical modality that can trigger immunogenic tumor cell death
R Nuccitelli, A McDaniel, S Anand, J Cha… - … for immunotherapy of …, 2017 - Springer
Background We have been develo** a non-thermal, drug-free tumor therapy called Nano-
Pulse Stimulation (NPS) that delivers ultrashort electric pulses to tumor cells which …
Pulse Stimulation (NPS) that delivers ultrashort electric pulses to tumor cells which …
Zearalenone induces apoptosis and necrosis in porcine granulosa cells via a caspase‐3‐and caspase‐9‐dependent mitochondrial signaling pathway
L Zhu, H Yuan, C Guo, Y Lu, S Deng… - Journal of cellular …, 2012 - Wiley Online Library
Zearalenone is a mycotoxin produced mainly by Fusarium. There are numerous incidences
of mycotoxicosis in laboratory and domestic animals, especially in pigs. However, little is …
of mycotoxicosis in laboratory and domestic animals, especially in pigs. However, little is …
Effect of microvesicles from Moringa oleifera containing miRNA on proliferation and apoptosis in tumor cell lines
M Potestà, V Roglia, M Fanelli, E Pietrobono… - Cell death …, 2020 - nature.com
Human microvesicles are key mediators of cell–cell communication. Exosomes function as
microRNA transporters, playing a crucial role in physiological and pathological processes …
microRNA transporters, playing a crucial role in physiological and pathological processes …