Regulation and functions of non-m6A mRNA modifications
Nucleobase modifications are prevalent in eukaryotic mRNA and their discovery has
resulted in the emergence of epitranscriptomics as a research field. The most abundant …
resulted in the emergence of epitranscriptomics as a research field. The most abundant …
Detection technologies for RNA modifications
Y Zhang, L Lu, X Li - Experimental & Molecular Medicine, 2022 - nature.com
To date, more than 170 chemical modifications have been characterized in RNA, providing a
new layer of gene expression regulation termed the 'epitranscriptome'. RNA modification …
new layer of gene expression regulation termed the 'epitranscriptome'. RNA modification …
Absolute quantification of single-base m6A methylation in the mammalian transcriptome using GLORI
C Liu, H Sun, Y Yi, W Shen, K Li, Y ** DNA and RNA modifications
Y Kong, EA Mead, G Fang - Nature Reviews Genetics, 2023 - nature.com
Chemical modifications to nucleic acids occur across the kingdoms of life and carry
important regulatory information. Reliable high-resolution map** of these modifications is …
important regulatory information. Reliable high-resolution map** of these modifications is …
Regulation of gene expression by m6Am RNA modification
B Cesaro, M Tarullo, A Fatica - International Journal of Molecular …, 2023 - mdpi.com
The field of RNA modification, also referred to as “epitranscriptomics,” is gaining more and
more interest from the scientific community. More than 160 chemical modifications have …
more interest from the scientific community. More than 160 chemical modifications have …
Global loss of cellular m6A RNA methylation following infection with different SARS-CoV-2 variants
Insights into host–virus interactions during SARS-CoV-2 infection are needed to understand
COVID-19 pathogenesis and may help to guide the design of novel antiviral therapeutics. N …
COVID-19 pathogenesis and may help to guide the design of novel antiviral therapeutics. N …
The CTBP2-PCIF1 complex regulates m6Am modification of mRNA in head and neck squamous cell carcinoma
K Li, J Chen, C Zhang, M Cheng… - The Journal of …, 2023 - Am Soc Clin Investig
PCIF1 can mediate the methylation of N 6, 2′-O-dimethyladenosine (m6Am) in mRNA. Yet,
the detailed interplay between PCIF1 and the potential cofactors and its pathological …
the detailed interplay between PCIF1 and the potential cofactors and its pathological …
[HTML][HTML] Enhancer RNA promotes resistance to radiotherapy in bone-metastatic prostate cancer by m6A modification
Rationale: Prostate cancer metastasizes to the bone with the highest frequency and exhibits
high resistance to 177 Lu-prostate-specific membrane antigen (PSMA) radioligand therapy …
high resistance to 177 Lu-prostate-specific membrane antigen (PSMA) radioligand therapy …