International consensus statement on allergy and rhinology: Allergic rhinitis–2023

SK Wise, C Damask, LT Roland, C Ebert… - International forum of …, 2023 - Wiley Online Library
Background In the 5 years that have passed since the publication of the 2018 International
Consensus Statement on Allergy and Rhinology: Allergic Rhinitis (ICAR‐Allergic Rhinitis …

International consensus statement on allergy and rhinology: allergic rhinitis

SK Wise, SY Lin, E Toskala, RR Orlandi… - International forum of …, 2018 - Wiley Online Library
Background Critical examination of the quality and validity of available allergic rhinitis (AR)
literature is necessary to improve understanding and to appropriately translate this …

Refining epigenetic prediction of chronological and biological age

E Bernabeu, DL McCartney, DA Gadd, RF Hillary… - Genome Medicine, 2023 - Springer
Background Epigenetic clocks can track both chronological age (cAge) and biological age
(bAge). The latter is typically defined by physiological biomarkers and risk of adverse health …

Genomic prediction of breeding values using a subset of SNPs identified by three machine learning methods

B Li, N Zhang, YG Wang, AW George, A Reverter… - Frontiers in …, 2018 - frontiersin.org
The analysis of large genomic data is hampered by issues such as a small number of
observations and a large number of predictive variables (commonly known as “large P small …

Cohort profile: pregnancy and childhood epigenetics (PACE) consortium

JF Felix, BR Joubert, AA Baccarelli… - International journal …, 2018 - academic.oup.com
Epigenetics refers to mitotically heritable changes to the DNA, which do not affect the DNA
sequence, but can influence its function. Currently, DNA methylation is the most studied …

Male sex is strongly associated with IgE-sensitization to airborne but not food allergens: results up to age 24 years from the BAMSE birth cohort

E Melén, A Bergström, I Kull, C Almqvist… - Clinical and translational …, 2020 - Springer
Background Up to half of the population in high-income countries has allergen-specific IgE
antibodies. However, data regarding sex differences of IgE-sensitization from childhood to …

Cohort profile: the Isle of Wight whole population birth cohort (IOWBC)

SH Arshad, JW Holloway, W Karmaus… - International journal …, 2018 - academic.oup.com
By the late 1980s, it was clear that allergic diseases, including asthma, eczema, allergic
rhinitis and food allergy, had been increasing in recent decades, but the extent of this …

[HTML][HTML] Transgenerational and intergenerational epigenetic inheritance in allergic diseases

TM Knudsen, FI Rezwan, Y Jiang, W Karmaus… - Journal of Allergy and …, 2018 - Elsevier
It has become clear that early life (including in utero exposures) is a key window of
vulnerability during which environmental exposures can alter developmental trajectories …

CRISPR-DT: designing gRNAs for the CRISPR-Cpf1 system with improved target efficiency and specificity

H Zhu, C Liang - Bioinformatics, 2019 - academic.oup.com
Abstract Motivation The Clustered Regularly Interspaced Short Palindromic Repeats
(CRISPR)-Cpf1 system has been successfully applied in genome editing. However, target …

Epigenome-wide meta-analysis of blood DNA methylation in newborns and children identifies numerous loci related to gestational age

SK Merid, A Novoloaca, GC Sharp, LK Küpers… - Genome medicine, 2020 - Springer
Background Preterm birth and shorter duration of pregnancy are associated with increased
morbidity in neonatal and later life. As the epigenome is known to have an important role …