A pile of pipelines: An overview of the bioinformatics software for metabarcoding data analyses
Environmental DNA (eDNA) metabarcoding has gained growing attention as a strategy for
monitoring biodiversity in ecology. However, taxa identifications produced through …
monitoring biodiversity in ecology. However, taxa identifications produced through …
Extensible benchmarking of methods that identify and quantify polyadenylation sites from RNA-seq data
The tremendous rate with which data is generated and analysis methods emerge makes it
increasingly difficult to keep track of their domain of applicability, assumptions, limitations …
increasingly difficult to keep track of their domain of applicability, assumptions, limitations …
Evaluation of a wastewater-based epidemiological approach to estimate the prevalence of SARS-CoV-2 infections and the detection of viral variants in disparate …
Background: Positive correlations have been reported between wastewater SARS-CoV-2
concentrations and a community's burden of infection, disease or both. However, previous …
concentrations and a community's burden of infection, disease or both. However, previous …
[HTML][HTML] A trait-based ecological perspective on the soil microbial antibiotic-related genetic machinery
Antibiotic resistance crisis dictates the need for resistance monitoring and the search for new
antibiotics. The development of monitoring protocols is hindered by the great diversity of …
antibiotics. The development of monitoring protocols is hindered by the great diversity of …
The evolutionary potential of influenza A virus hemagglutinin is highly constrained by epistatic interactions with neuraminidase
Antigenic evolution of the influenza A virus (IAV) hemagglutinin (HA) gene limits efforts to
effectively control the spread of the virus in the population. Efforts to understand the …
effectively control the spread of the virus in the population. Efforts to understand the …
Genome wide association study of Escherichia coli bloodstream infection isolates identifies genetic determinants for the portal of entry but not fatal outcome
E Denamur, B Condamine, M Esposito-Farese… - PLoS …, 2022 - journals.plos.org
Escherichia coli is an important cause of bloodstream infections (BSI), which is of concern
given its high mortality and increasing worldwide prevalence. Finding bacterial genetic …
given its high mortality and increasing worldwide prevalence. Finding bacterial genetic …
Building a FAIR image data ecosystem for microscopy communities
I Kemmer, A Keppler, B Serrano-Solano… - Histochemistry and Cell …, 2023 - Springer
Bioimaging has now entered the era of big data with faster-than-ever development of
complex microscopy technologies leading to increasingly complex datasets. This enormous …
complex microscopy technologies leading to increasingly complex datasets. This enormous …
[HTML][HTML] ETHOS. PASSION: An open-source workflow for rooftop photovoltaic potential assessments from satellite imagery
The assessment of rooftop photovoltaic potential has become increasingly accurate due to
the expanding availability of satellite imagery and improvements in computer vision …
the expanding availability of satellite imagery and improvements in computer vision …
Conserved regulatory motifs in the juxtamembrane domain and kinase N-lobe revealed through deep mutational scanning of the MET receptor tyrosine kinase domain
GO Estevam, EM Linossi, CB Macdonald, CA Espinoza… - Elife, 2024 - elifesciences.org
MET is a receptor tyrosine kinase (RTK) responsible for initiating signaling pathways
involved in development and wound repair. MET activation relies on ligand binding to the …
involved in development and wound repair. MET activation relies on ligand binding to the …
A constitutive interferon-high immunophenotype defines response to immunotherapy in colorectal cancer
Fewer than 50% of metastatic deficient mismatch repair (dMMR) colorectal cancer (CRC)
patients respond to immune checkpoint inhibition (ICI). Identifying and expanding this …
patients respond to immune checkpoint inhibition (ICI). Identifying and expanding this …