Causal associations between gut microbiota and primary biliary cholangitis: a bidirectional two-sample Mendelian randomization study

J Zhang, G Wu, Y Tang, H Liu, X Ge, R Peng… - Frontiers in …, 2023 - frontiersin.org
Background Previous studies have suggested an association between gut microbiota and
primary biliary cholangitis (PBC). Nonetheless, the causal relationship between gut …

Explore key genes of Crohn's disease based on glycerophospholipid metabolism: A comprehensive analysis Utilizing Mendelian Randomization, Multi-Omics …

C Chen, J Quan, X Chen, T Yang, C Yu, S Ye… - International …, 2024 - Elsevier
Abstract Background and Aims Crohn's disease (CD) is a chronic, complex inflammatory
condition with increasing incidence and prevalence worldwide. However, the causes of CD …

Causal relationship between systemic lupus erythematosus and primary liver cirrhosis based on two-sample bidirectional Mendelian randomization and transcriptome …

L Wu, S Li, C Wu, S Wu, Y Lin, D Wei - Arthritis Research & Therapy, 2024 - Springer
Background Overlap** cases of systemic lupus erythematosus (SLE) and primary biliary
cirrhosis (PBC) are rare and have not yet been fully proven to be accidental or have a …

Association between diabetes mellitus and primary biliary cholangitis: a two-sample Mendelian randomization study

D Lv, H Wang, Y Leng, S Chen, H Sun… - Frontiers in …, 2024 - frontiersin.org
Background Previous observational studies have demonstrated a link between diabetes
mellitus (DM) and primary biliary cholangitis (PBC). Nevertheless, since these relationships …

[HTML][HTML] Primary Biliary Cholangitis Associated with Ulcerative Colitis: Case Series and Literature Review

Q Li, Y Zong - Medicina, 2024 - mdpi.com
Purpose: To study the coexistence of ulcerative colitis (UC) and primary biliary cholangitis
(PBC). Methods: The Bei**g Friendship Hospital patient database was explored to identify …

Dissecting causal relationships between primary biliary cholangitis and extrahepatic autoimmune diseases based on Mendelian randomization

G Ma, J Yang, X Wang, E **a, J Yu, M Zhang, Y Hu… - Scientific Reports, 2024 - nature.com
As an autoimmune disease, up to 73% of patients with primary biliary cholangitis (PBC)
have a combination of extrahepatic autoimmune diseases (EHAIDs); however, the causal …

Causal effect between gut microbiota and metabolic syndrome in European population: a bidirectional mendelian randomization study

J Yan, Z Wang, G Bao, C Xue, W Zheng, R Fu… - Cell & Bioscience, 2024 - Springer
Background Observational studies have reported that gut microbiota composition is
associated with metabolic syndrome. However, the causal effect of gut microbiota on …

Genetic association and causal relationship between multiple modifiable risk factors and autoimmune liver disease: a two-sample mendelian randomization study

W Gao, C Peng, Z Wang, Y Li, M Liu - Journal of Translational Medicine, 2024 - Springer
Background The intricate etiology of autoimmune liver disease (AILD) involves genetic,
environmental, and other factors that yet to be completely elucidated. This study …

Causal association of inflammatory bowel disease with sarcoidosis and the mediating role of primary biliary cholangitis

J Yi, S Wu, H He - Frontiers in Immunology, 2024 - frontiersin.org
Objectives Previous observational epidemiological studies have identified a potential
association between inflammatory bowel disease (IBD) and sarcoidosis. Nonetheless, the …

[HTML][HTML] Investigating shared genetic architecture between inflammatory bowel diseases and primary biliary cholangitis

W Huang, R Jiang, S Li, R Zeng, Y Li, Y Zhang, S Tong… - JHEP Reports, 2024 - Elsevier
Background & Aims Inflammatory bowel disease (IBD) is commonly associated with
extraintestinal complications, including autoimmune liver disease. The co-occurrence of IBD …