Obesity and overweight have become serious health problems in the world and are linked to
a variety of metabolic disorders. Phytochemicals with a weight-loss effect have been widely …

Covering: 1977 to present Arsenic is widely distributed throughout terrestrial and aquatic
environments, mainly in highly toxic inorganic forms. To adapt to environmental inorganic …

N-Methylated amino acids (N-MeAAs) are privileged residues of naturally occurring peptides
critical to bioactivity. However, de novo discovery from ribosome display is limited by poor …

Glycolytic interconversion of phosphoglycerate isomers is catalysed in numerous
pathogenic microorganisms by a cofactor-independent mutase (iPGM) structurally distinct …

Many bacteria secrete cellulose, which forms the structural basis for bacterial multicellular
aggregates, termed biofilms. The cellulose synthase complex of Salmonella typhimurium …

The unique bioactivities of arsenic-containing secondary metabolites have been revealed
recently, but studies on arsenic secondary metabolism in microorganisms have been …

Phosphoglycerate mutases (PGAMs) catalyse the reversible isomerisation of 3‐
phosphoglycerate and 2‐phosphoglycerate, a step of glycolysis. PGAMs can be sub‐divided …

Catalysis of human phosphoglycerate mutase is dependent on a 2, 3-bisphosphoglycerate
cofactor (dPGM), whereas the nonhomologous isozyme in many parasitic species is cofactor …

Abstract The 2, 3-bisphosphoglycerate-independent phosphoglycerate mutase (iPGAM) has
been identified as a crucial regulating key point in the carbon storage metabolism of …

Cofactor-independent phosphoglycerate mutase has been proposed as a therapeutic target
for the treatment of trypanosomatid diseases. In this paper, we report the identification of …