This paper describes a data organization system and genuine content-addressable memory
called the WEBSOM. It is a two-layer self-organizing map (SOM) architecture where …

Amyloid β peptide (Aβ) is the major constituent of extracellular plaques and perivascular
amyloid deposits, the pathognomonic neuropathological lesions of Alzheimer's disease. Cu …

Over the past two decades, prokaryotic expression systems have been widely exploited for
the bioproduction of many therapeutic proteins. Much of the success can be attributed to the …

Physiologic relaxation of vascular smooth muscle is induced by the cyclic guanosine
monophosphate (cGMP)-dependent protein kinase Iα enzyme (cGKIα), which activates …

c-Jun N-terminal kinase (JNK)-mediated cell signaling pathways are regulated
endogenously in part by protein-protein interactions with glutathione S-transferase P1–1 …

A structural investigation of the sodium dodecyl sulfate (SDS)-induced fibrillation of α-
synuclein (αSN), a 140-amino-acid protein implicated in Parkinson's disease, has been …

This research was to explore the mechanism of ultrasonic impact on protease activity. The
effects of energy-gathered ultrasound on the activity, kinetics, thermodynamics and …

Bone sialoprotein (BSP) is a highly modified, anionic phosphoprotein that is expressed
almost exclusively in mineralizing connective tissues and has been shown to be a potent …

An olfactory receptor has been expressed in bacterial cells as a fusion protein with
glutathione S-transferase (GST). Overexpression of receptor protein yielding about 10% of …

Given that α-synuclein has been implicated in the pathogenesis of several
neurodegenerative disorders, deciphering the structure of this protein is of particular …