Thrombotic microangiopathy (TMA), a pathological lesion observed in a wide spectrum of
diseases, is triggered by endothelial injury and/or dysfunction. Although TMA lesions are …

Preeclampsia, a systemic vascular disorder characterized by new-onset hypertension and
proteinuria after 20 weeks of gestation, is the leading cause of maternal and perinatal …

Acute kidney injury (AKI) is a major kidney disease characterized by an abrupt loss of renal
function. Accumulating evidence indicates that incomplete or maladaptive repair after AKI …

Patients are exposed to numerous prescribed and over-the-counter medications.
Unfortunately, drugs remain a relatively common cause of acute and chronic kidney injury. A …

Age-related macular degeneration (AMD) is a disease that affects the macula–the central
part of the retina. It is a leading cause of irreversible vision loss in the elderly. AMD onset is …

Inhibition of vascular endothelial growth factor A (VEGFA)/vascular endothelial growth factor
receptor 2 (VEGFR2) signaling is a common therapeutic strategy in oncology, with new …

The kidney is permeated by a highly complex vascular system with glomerular and
peritubular capillary networks that are essential for maintaining the normal functions of …

Edema stemming from leaky blood vessels is common in eye diseases such as age-related
macular degeneration and diabetic retinopathy. Whereas therapies targeting vascular …

Objective Aiming to investigate diabetic retinopathy (DR) risk factors and predictive models
by machine learning using a large sample dataset. Design Retrospective study based on a …

Secondary hemolytic uremic syndrome (HUS) is a heterogeneous group of thrombotic
microangiopathies associated with various underlying conditions. Whether it belongs to the …