Hydrophobic drugs exhibit altered bioavailability and pose other challenges at an industrial
level due to their poor solubility and dissolution rates. In addition, poor flowability …

Appropriate selection of excipient grade during tablet formulation development depends on
thorough knowledge in their compaction and flow properties. Each chemically unique …

In this paper, a new parameter highly relevant to tablet friability is proposed based on a
systematical study of the tablet quality attributes and texture performances of five different …

The effect of tablet tensile strength, drop height, number of drops and formulation on the
propensity of tablet defects was investigated using modified tablet drop tests. It was found …

Based on the similarity between the solidification process of the Additive Manufacturing (AM)
binder jetting technique and wet granulation mechanisms, binder jetting is used to print …

Accelerator-based techniques with electromagnetic mass separation are considered among
the most innovative and promising strategies to produce non-conventional radionuclides for …

A bi-directional coupling between the Discrete Element Method (DEM) and Population
Balance Modelling (PBM) is suggested to model the failure of pharmaceutical tablets under …

Pharmaceutical tablets can be susceptible to damage such as edge chip** or erosion of
the core during the tablet coating process. The intersection of certain process parameters …

Discrete element method simulations are conducted to probe the various regimes of
postimpact behavior of particles with solid surfaces. The impacting particles are described …

Solid dispersion (SD) systems have been extensively used to increase the dissolution and
bioavailability of poorly water-soluble drugs. To circumvent the limitations of …