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Biomaterials tools to modulate the tumour microenvironment in immunotherapy
Y Chao, Z Liu - Nature Reviews Bioengineering, 2023 - nature.com
Cancer immunotherapies, such as immune checkpoint blockade and chimeric antigen
receptor (CAR) T cell therapy, have transformed clinical oncology. However, limited patient …
receptor (CAR) T cell therapy, have transformed clinical oncology. However, limited patient …
Responsive biomaterials: optimizing control of cancer immunotherapy
Immunotherapy has emerged as an eminent and effective modality in the treatment of
cancer. However, current cancer immunotherapies lack spatial and temporal control …
cancer. However, current cancer immunotherapies lack spatial and temporal control …
Rational design of immunomodulatory hydrogels for chronic wound healing
With all the advances in tissue engineering for construction of fully functional skin tissue,
complete regeneration of chronic wounds is still challenging. Since immune reaction to the …
complete regeneration of chronic wounds is still challenging. Since immune reaction to the …
Translational applications of hydrogels
Advances in hydrogel technology have unlocked unique and valuable capabilities that are
being applied to a diverse set of translational applications. Hydrogels perform functions …
being applied to a diverse set of translational applications. Hydrogels perform functions …
Tumor‐microenvironment‐responsive nanomedicine for enhanced cancer immunotherapy
The past decades have witnessed great progress in cancer immunotherapy, which has
profoundly revolutionized oncology, whereas low patient response rates and potential …
profoundly revolutionized oncology, whereas low patient response rates and potential …
ROS-scavenging hydrogel to promote healing of bacteria infected diabetic wounds
Bacterial infection has been a great threat to dermal wounds, especially to difficult-to-heal
diabetic wounds. It is known that reactive oxygen species (ROS) generated by wounds or …
diabetic wounds. It is known that reactive oxygen species (ROS) generated by wounds or …
Bioengineered nanogels for cancer immunotherapy
Recent years have witnessed increasingly rapid advances in nanocarrier-based
biomedicine aimed at improving treatment paradigms for cancer. Nanogels serve as …
biomedicine aimed at improving treatment paradigms for cancer. Nanogels serve as …
Reactive oxygen species (ROS)-based nanomedicine
B Yang, Y Chen, J Shi - Chemical reviews, 2019 - ACS Publications
Reactive oxygen species (ROS) play an essential role in regulating various physiological
functions of living organisms. The intrinsic biochemical properties of ROS, which underlie …
functions of living organisms. The intrinsic biochemical properties of ROS, which underlie …
Hydrogel drug delivery systems for minimally invasive local immunotherapy of cancer
Although systemic immunotherapy has achieved durable responses and improved survival
for certain patients and cancer types, low response rates and immune system-related …
for certain patients and cancer types, low response rates and immune system-related …
Hydrogel-based controlled drug delivery for cancer treatment: a review
As an emerging drug carrier, hydrogels have been widely used for tumor drug delivery. A
hydrogel drug carrier can cause less severe side effects than systemic chemotherapy and …
hydrogel drug carrier can cause less severe side effects than systemic chemotherapy and …