Increasing evidence suggests that abnormal cerebral glucose metabolism is largely present
in Alzheimer's disease (AD). The brain utilizes glucose as its main energy source and a …

Neurodegenerative diseases (NDs) such as Alzheimer disease (AD), Parkinson disease
(PD), and Huntington disease (HD) represent a major socio-economic challenge in view of …

Alzheimer disease is a progressive neurodegenerative disorder, mainly affecting older
people, which severely impairs patients' quality of life. In the recent years, the number of …

Alzheimer's disease (AD) is a neurodegenerative disorder that usually develops slowly and
progressively worsens over time. Although there has been increasing research interest in …

Vitamin D may have multiple effects on the nervous system and its deficiency can represent
a possible risk factor for the development of many neurological diseases. Recent studies are …

Mitochondrial dysfunction in neurons has recently become a promising therapeutic target for
Alzheimer's disease (AD). Regulation of dysfunctional mitochondria through multiple …

The development of new therapeutic approaches to diseases relies on the identification of
key molecular targets involved in amplifying disease processes. One such molecule is …

Alzheimer's disease, one of the most common forms of dementia, is characterized by a slow
progression of cognitive impairment and neuronal loss. Currently, approved treatments for …

The aging process is accompanied by critical changes in cellular and molecular functions,
which upset the homeostatic balance in the central nervous system. Accumulation of metals …

Synaptic plasticity is believed to underlie the cellular and molecular basis of memory
formation. Mitochondria are one of the main organelles involved in metabolism and energy …