Anti-inflammatory effects of omega-3 fatty acids in the brain: physiological mechanisms and relevance to pharmacology

S Laye, A Nadjar, C Joffre, RP Bazinet - Pharmacological reviews, 2018 - Elsevier
Classically, polyunsaturated fatty acids (PUFA) were largely thought to be relatively inert
structural components of brain, largely important for the formation of cellular membranes …

Protectins and maresins: New pro-resolving families of mediators in acute inflammation and resolution bioactive metabolome

CN Serhan, J Dalli, RA Colas, JW Winkler… - Biochimica et Biophysica …, 2015 - Elsevier
Acute inflammatory responses are protective, yet without timely resolution can lead to
chronic inflammation and organ fibrosis. A systems approach to investigate self-limited (self …

[HTML][HTML] Macrophage proresolving mediator maresin 1 stimulates tissue regeneration and controls pain

CN Serhan, J Dalli, S Karamnov, A Choi… - The FASEB …, 2012 - pmc.ncbi.nlm.nih.gov
Self-resolving inflammatory exudates and lipid mediator metabolomics recently uncovered a
new family of potent anti-inflammatory and proresolving mediators biosynthesized by …

Resolvin E1 and protectin D1 activate inflammation-resolution programmes

JM Schwab, N Chiang, M Arita, CN Serhan - Nature, 2007 - nature.com
Resolution of acute inflammation is an active process essential for appropriate host
responses, tissue protection and the return to homeostasis,,. During resolution, specific …

Resolution phase of inflammation: novel endogenous anti-inflammatory and proresolving lipid mediators and pathways

CN Serhan - Annu. Rev. Immunol., 2007 - annualreviews.org
Resolution of inflammation and the return of tissues to homeostasis are essential. Efforts to
identify molecular events governing termination of self-limited inflammation uncovered …

Chemistry of the retinoid (visual) cycle

PD Kiser, M Golczak, K Palczewski - Chemical reviews, 2014 - ACS Publications
As succinctly summarized by Wolf, 1 lack of vitamin A (all-trans-retinol) was recognized by
ancient Egyptians as causing a visual deficiency involving the retina and cornea that could …

[HTML][HTML] Dietary (n-3) fatty acids and brain development1

SM Innis - The Journal of nutrition, 2007 - Elsevier
Abstract The (n-3) fatty acids are essential dietary nutrients, and one of their important roles
is providing docosahexaenoic acid [22: 6 (n-3)](DHA) for growth and function of nervous …

Dietary omega 3 fatty acids and the develo** brain

SM Innis - Brain research, 2008 - Elsevier
The ω-3 fatty acids are essential dietary nutrients and one of their important roles is
providing the fatty acid with 22 carbons and 6 double bonds known as docosahexaenoic …

Docosahexaenoic acid (DHA), a fundamental fatty acid for the brain: New dietary sources

F Echeverría, R Valenzuela… - … and Essential Fatty …, 2017 - Elsevier
Abstract Docosahexaenoic acid (C22: 6n-3, DHA) is a long-chain polyunsaturated fatty acid
of marine origin fundamental for the formation and function of the nervous system …

Docosahexaenoic acid signalolipidomics in nutrition: significance in aging, neuroinflammation, macular degeneration, Alzheimer's, and other neurodegenerative …

NG Bazan, MF Molina, WC Gordon - Annual review of nutrition, 2011 - annualreviews.org
Essential polyunsaturated fatty acids (PUFAs) are critical nutritional lipids that must be
obtained from the diet to sustain homeostasis. Omega-3 and-6 PUFAs are key components …