Trophic effects of mesenchymal stem cells in tissue regeneration

Y Fu, L Karbaat, L Wu, J Leijten, SK Both… - … Engineering Part B …, 2017 - liebertpub.com
Mesenchymal stem cells (MSCs) are considered to hold great therapeutic value for cell-
based therapy and for tissue regeneration in particular. Recent evidence indicates that the …

Peering into tunneling nanotubes—The path forward

D Cordero Cervantes, C Zurzolo - The EMBO Journal, 2021 - embopress.org
Abstract The identification of Tunneling Nanotubes (TNTs) and TNT‐like structures signified
a critical turning point in the field of cell‐cell communication. With hypothesized roles in …

Cell connections by tunneling nanotubes: effects of mitochondrial trafficking on target cell metabolism, homeostasis, and response to therapy

ML Vignais, A Caicedo, JM Brondello… - Stem cells …, 2017 - Wiley Online Library
Intercellular communications play a major role in tissue homeostasis and responses to
external cues. Novel structures for this communication have recently been described. These …

Role of tunneling nanotubes in viral infection, neurodegenerative disease, and cancer

V Tiwari, R Koganti, G Russell, A Sharma… - Frontiers in …, 2021 - frontiersin.org
The network of tunneling nanotubes (TNTs) represents the filamentous (F)-actin rich tubular
structure which is connected to the cytoplasm of the adjacent and or distant cells to mediate …

B-cell precursor acute lymphoblastic leukemia cells use tunneling nanotubes to orchestrate their microenvironment

R Polak, B de Rooij, R Pieters… - Blood, The Journal of …, 2015 - ashpublications.org
Acute lymphoblastic leukemia (ALL) cells reside in the bone marrow microenvironment
which nurtures and protects cells from chemotherapeutic drugs. The disruption of cell-cell …

Targeting vascular and leukocyte communication in angiogenesis, inflammation and fibrosis

J Kreuger, M Phillipson - Nature Reviews Drug Discovery, 2016 - nature.com
Regulation of vascular permeability, recruitment of leukocytes from blood to tissue and
angiogenesis are all processes that occur at the level of the microvasculature during both …

Potential role of the formation of tunneling nanotubes in HIV-1 spread in macrophages

M Hashimoto, F Bhuyan, M Hiyoshi… - The Journal of …, 2016 - journals.aai.org
Tunneling nanotubes (TNTs), the long membrane extensions connecting distant cells, have
emerged as a novel form of cell-to-cell communication. However, it is not fully understood …

Tunnelling nanotube formation is driven by Eps8/IRSp53‐dependent linear actin polymerization

JM Henderson, N Ljubojevic, S Belian, T Chaze… - The EMBO …, 2023 - embopress.org
Tunnelling nanotubes (TNTs) connect distant cells and mediate cargo transfer for
intercellular communication in physiological and pathological contexts. How cells generate …

Extracellular vesicles, tunneling nanotubes, and cellular interplay: synergies and missing links

M Nawaz, F Fatima - Frontiers in molecular biosciences, 2017 - frontiersin.org
The process of intercellular communication seems to have been a highly conserved
evolutionary process. Higher eukaryotes use several means of intercellular communication …

Tunneling nanotubes and related structures: molecular mechanisms of formation and function

S Dagar, D Pathak, HV Oza… - Biochemical …, 2021 - portlandpress.com
Tunneling nanotubes (TNTs) are F-actin-based, membrane-enclosed tubular connections
between animal cells that transport a variety of cellular cargo. Over the last 15 years since …