Small RNAs, large networks: posttranscriptional regulons in gram-negative bacteria
Small regulatory RNA (sRNAs) are key mediators of posttranscriptional gene control in
bacteria. Assisted by RNA-binding proteins, a single sRNA often modulates the expression …
bacteria. Assisted by RNA-binding proteins, a single sRNA often modulates the expression …
Antimicrobial resistance and mechanisms of epigenetic regulation
X Wang, D Yu, L Chen - Frontiers in Cellular and Infection …, 2023 - frontiersin.org
The rampant use of antibiotics in animal husbandry, farming and clinical disease treatment
has led to a significant issue with pathogen resistance worldwide over the past decades …
has led to a significant issue with pathogen resistance worldwide over the past decades …
Plasmids manipulate bacterial behaviour through translational regulatory crosstalk
Beyond their role in horizontal gene transfer, conjugative plasmids commonly encode
homologues of bacterial regulators. Known plasmid regulator homologues have highly …
homologues of bacterial regulators. Known plasmid regulator homologues have highly …
Bacterial RNA chaperones and chaperone-like riboregulators: behind the scenes of RNA-mediated regulation of cellular metabolism
In all domains of life, RNA chaperones safeguard and guide the fate of the cellular RNA
pool. RNA chaperones comprise structurally diverse proteins that ensure proper folding …
pool. RNA chaperones comprise structurally diverse proteins that ensure proper folding …
Structural basis for recognition of transcriptional terminator structures by ProQ/FinO domain RNA chaperones
HJ Kim, M Black, RA Edwards… - Nature …, 2022 - nature.com
Abstract The ProQ/FinO family of RNA binding proteins mediate sRNA-directed gene
regulation throughout gram-negative bacteria. Here, we investigate the structural basis for …
regulation throughout gram-negative bacteria. Here, we investigate the structural basis for …
Riboregulation in bacteria: From general principles to novel mechanisms of the trp attenuator and its sRNA and peptide products
E Evguenieva‐Hackenberg - Wiley Interdisciplinary Reviews …, 2022 - Wiley Online Library
Gene expression strategies ensuring bacterial survival and competitiveness rely on cis‐and
trans‐acting RNA‐regulators (riboregulators). Among the cis‐acting riboregulators are …
trans‐acting RNA‐regulators (riboregulators). Among the cis‐acting riboregulators are …
Impacts of small RNAs and their chaperones on bacterial pathogenicity
L Djapgne, AG Oglesby - Frontiers in Cellular and Infection …, 2021 - frontiersin.org
Bacterial small RNAs (sRNAs) are critical post-transcriptional regulators that exert broad
effects on cell physiology. One class of sRNAs, referred to as trans-acting sRNAs, base-pairs …
effects on cell physiology. One class of sRNAs, referred to as trans-acting sRNAs, base-pairs …
FinO/ProQ-family proteins: an evolutionary perspective
Z Liao, A Smirnov - Bioscience reports, 2023 - portlandpress.com
RNA-binding proteins are key actors of post-transcriptional networks. Almost exclusively
studied in the light of their interactions with RNA ligands and the associated functional …
studied in the light of their interactions with RNA ligands and the associated functional …
ProQ-associated small RNAs control motility in Vibrio cholerae
R Ghandour, D Devlitsarov, P Popp… - Nucleic Acids …, 2024 - academic.oup.com
Gene regulation at the post-transcriptional level is prevalent in all domains of life. In bacteria,
ProQ-like proteins have emerged as important RNA chaperones facilitating RNA stability …
ProQ-like proteins have emerged as important RNA chaperones facilitating RNA stability …
Scanning mutagenesis of RNA-binding protein ProQ reveals a quality control role for the Lon protease
The FinO-domain protein ProQ belongs to a widespread family of RNA-binding proteins
(RBPs) involved in gene regulation in bacterial chromosomes and mobile elements. While …
(RBPs) involved in gene regulation in bacterial chromosomes and mobile elements. While …