Mechanisms of NAFLD development and therapeutic strategies
There has been a rise in the prevalence of nonalcoholic fatty liver disease (NAFLD),
paralleling a worldwide increase in diabetes and metabolic syndrome. NAFLD, a continuum …
paralleling a worldwide increase in diabetes and metabolic syndrome. NAFLD, a continuum …
[PDF][PDF] Role of cholesterol‐associated steatohepatitis in the development of NASH
CL Horn, AL Morales, C Savard… - Hepatology …, 2022 - Wiley Online Library
The rising prevalence of nonalcoholic fatty liver disease (NAFLD) and NAFLD‐related
cirrhosis in the United States and globally highlights the need to better understand the …
cirrhosis in the United States and globally highlights the need to better understand the …
[HTML][HTML] A diet-induced animal model of non-alcoholic fatty liver disease and hepatocellular cancer
Background & Aims The lack of a preclinical model of progressive non-alcoholic
steatohepatitis (NASH) that recapitulates human disease is a barrier to therapeutic …
steatohepatitis (NASH) that recapitulates human disease is a barrier to therapeutic …
Preclinical models of non-alcoholic fatty liver disease
Non-alcoholic fatty liver disease (NAFLD) can manifest as non-alcoholic fatty liver (NAFL) or
non-alcoholic steatohepatitis (NASH). NASH is often associated with progressive fibrosis …
non-alcoholic steatohepatitis (NASH). NASH is often associated with progressive fibrosis …
[HTML][HTML] Animal models of NAFLD from a hepatologist's point of view
D Jahn, S Kircher, HM Hermanns, A Geier - Biochimica et Biophysica Acta …, 2019 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) is a chronic liver disorder closely linked to obesity,
hyperlipidemia and type 2 diabetes and is increasingly recognized as a major health …
hyperlipidemia and type 2 diabetes and is increasingly recognized as a major health …
In vitro and in vivo models of non-alcoholic fatty liver disease: a critical appraisal
PA Soret, J Magusto, C Housset… - Journal of clinical medicine, 2020 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD), including non-alcoholic fatty liver (NAFL) and non-
alcoholic steatohepatitis (NASH), represents the hepatic manifestation of obesity and …
alcoholic steatohepatitis (NASH), represents the hepatic manifestation of obesity and …
Insights into the epidemiology, pathogenesis, and therapeutics of nonalcoholic fatty liver diseases
Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease which affects≈
25% of the adult population worldwide, placing a tremendous burden on human health. The …
25% of the adult population worldwide, placing a tremendous burden on human health. The …
Fast food diet mouse: novel small animal model of NASH with ballooning, progressive fibrosis, and high physiological fidelity to the human condition
M Charlton, A Krishnan, K Viker… - American Journal …, 2011 - journals.physiology.org
Although there are small animal platforms that recapitulate some of the histological features
of nonalcoholic fatty liver disease, there are no small animal models of nonalcoholic …
of nonalcoholic fatty liver disease, there are no small animal models of nonalcoholic …
The pig as an animal model for human pathologies: A proteomics perspective
Traditional biomedical models are easy to manage in experimental facilities and allow fast
and affordable basic genetic studies related to human disorders, but in some cases they do …
and affordable basic genetic studies related to human disorders, but in some cases they do …
Animal models of nonalcoholic steatohepatitis: eat, delete, and inflame
With the obesity epidemic, nonalcoholic fatty liver disease (NAFLD) has become a public
health problem with increasing prevalence. The mechanism of disease progression remains …
health problem with increasing prevalence. The mechanism of disease progression remains …