Sarcopenic obesity in older adults: aetiology, epidemiology and treatment strategies

JA Batsis, DT Villareal - Nature Reviews Endocrinology, 2018 - nature.com
The prevalence of obesity in combination with sarcopenia (the age-related loss of muscle
mass and strength or physical function) is increasing in adults aged 65 years and older. A …

How many times per week should a muscle be trained to maximize muscle hypertrophy? A systematic review and meta-analysis of studies examining the effects of …

BJ Schoenfeld, J Grgic, J Krieger - Journal of sports sciences, 2019 - Taylor & Francis
Training frequency is considered an important variable in the hypertrophic response to
regimented resistance exercise. The purpose of this paper was to conduct a systematic …

Impact of biological sex and sex hormones on molecular signatures of skeletal muscle at rest and in response to distinct exercise training modes

MW Pataky, S Dasari, KL Michie, KJ Sevits, AA Kumar… - Cell metabolism, 2023 - cell.com
Substantial divergence in cardio-metabolic risk, muscle size, and performance exists
between men and women. Considering the pivotal role of skeletal muscle in human …

Metformin blunts muscle hypertrophy in response to progressive resistance exercise training in older adults: A randomized, double‐blind, placebo‐controlled …

RG Walton, CM Dungan, DE Long, SC Tuggle… - Aging cell, 2019 - Wiley Online Library
Progressive resistance exercise training (PRT) is the most effective known intervention for
combating aging skeletal muscle atrophy. However, the hypertrophic response to PRT is …

Sarcopenia definition: does it really matter? Implications for resistance training

C Smith, MN Woessner, M Sim, I Levinger - Ageing Research Reviews, 2022 - Elsevier
The loss of muscle mass, strength and function, known as sarcopenia, is common in older
adults, and is associated with falls, fractures, cardiometabolic diseases, and lower quality of …

[HTML][HTML] The importance of resistance exercise training to combat neuromuscular aging

KM Lavin, BM Roberts, CS Fry, T Moro… - …, 2019 - journals.physiology.org
Older adults undergoing age-related decrements in muscle health can benefit substantially
from resistance exercise training, a potent stimulus for whole muscle and myofiber …

Defining anabolic resistance: implications for delivery of clinical care nutrition

RW Morton, DA Traylor, PJM Weijs… - Current opinion in …, 2018 - journals.lww.com
Insofar as atrophic loss of skeletal muscle mass is concerned, anabolic resistance is a
principal determinant of age-induced losses and appears to be a contributor to critical illness …

Effects of high‐intensity resistance training on osteopenia and sarcopenia parameters in older men with osteosarcopenia—one‐year results of the randomized …

W Kemmler, M Kohl, M Fröhlich, F Jakob… - Journal of Bone and …, 2020 - academic.oup.com
Dynamic resistance exercise (DRT) might be the most promising agent for fighting
sarcopenia in older people. However, the positive effect of DRT on osteopenia/osteoporosis …

Randomized, controlled trial of exercise on objective and subjective sleep in Parkinson's disease

AW Amara, KH Wood, A Joop, RA Memon… - Movement …, 2020 - Wiley Online Library
Background Sleep dysfunction is common and disabling in persons with Parkinson's
Disease (PD). Exercise improves motor symptoms and subjective sleep quality in PD, but …

State of knowledge on molecular adaptations to exercise in humans: historical perspectives and future directions

KM Lavin, PM Coen, LC Baptista… - Comprehensive …, 2022 - pmc.ncbi.nlm.nih.gov
For centuries, regular exercise has been acknowledged as a potent stimulus to promote,
maintain, and restore healthy functioning of nearly every physiological system of the human …