Comparative accuracy of biomarkers for the prediction of hospital-acquired acute kidney injury: a systematic review and meta-analysis
Background Several biomarkers have been proposed to predict the occurrence of acute
kidney injury (AKI); however, their efficacy varies between different trials. The aim of this …
kidney injury (AKI); however, their efficacy varies between different trials. The aim of this …
The multifaceted roles of neutrophil gelatinase associated lipocalin (NGAL) in inflammation and cancer
Neutrophil gelatinase associated lipocalin (NGAL), also known as oncogene 24p3,
uterocalin, siderocalin or lipocalin 2, is a 24kDa secreted glycoprotein originally purified …
uterocalin, siderocalin or lipocalin 2, is a 24kDa secreted glycoprotein originally purified …
The outcome of neutrophil gelatinase-associated lipocalin-positive subclinical acute kidney injury: a multicenter pooled analysis of prospective studies
Objectives: The aim of this study was to test the hypothesis that, without diagnostic changes
in serum creatinine, increased neutrophil gelatinase-associated lipocalin (NGAL) levels …
in serum creatinine, increased neutrophil gelatinase-associated lipocalin (NGAL) levels …
Urinary and serum biomarkers for the diagnosis of acute kidney injury: an in-depth review of the literature
J Vanmassenhove, R Vanholder… - Nephrology Dialysis …, 2013 - academic.oup.com
Background Acute kidney injury (AKI) remains associated with high morbidity and mortality,
despite progress in medical care. Although the RIFLE (Risk, Injury, Failure, Loss, End-Stage …
despite progress in medical care. Although the RIFLE (Risk, Injury, Failure, Loss, End-Stage …
Neutrophil gelatinase-associated lipocalin as a biomarker of acute kidney injury: a critical evaluation of current status
A Haase-Fielitz, M Haase… - Annals of clinical …, 2014 - journals.sagepub.com
Background The early prediction of acute kidney injury (AKI) by current clinical and
laboratory methods remains inadequate. Neutrophil gelatinase-associated lipocalin (NGAL) …
laboratory methods remains inadequate. Neutrophil gelatinase-associated lipocalin (NGAL) …
The rise and fall of NGAL in acute kidney injury
For many years, neutrophil gelatinase-associated lipocalin (NGAL) has been considered the
most promising biomarker of acute kidney injury (AKI). Commercial assays and point-of-care …
most promising biomarker of acute kidney injury (AKI). Commercial assays and point-of-care …
[HTML][HTML] Comparison of standard and accelerated initiation of renal replacement therapy in acute kidney injury
R Wald, NKJ Adhikari, OM Smith, MA Weir, K Pope… - Kidney international, 2015 - Elsevier
In patients with severe acute kidney injury (AKI) but no urgent indication for renal
replacement therapy (RRT), the optimal time to initiate RRT remains controversial. While …
replacement therapy (RRT), the optimal time to initiate RRT remains controversial. While …
Neutrophil gelatinase-associated lipocalin measured on clinical laboratory platforms for the prediction of acute kidney injury and the associated need for dialysis …
Rationale & Objective The usefulness of measures of neutrophil gelatinase-associated
lipocalin (NGAL) in urine or plasma obtained on clinical laboratory platforms for predicting …
lipocalin (NGAL) in urine or plasma obtained on clinical laboratory platforms for predicting …
Diagnosis of acute kidney injury using functional and injury biomarkers: workgroup statements from the tenth Acute Dialysis Quality Initiative Consensus Conference
Acute kidney injury (AKI) commonly occurs in hospitalized patients and is independently and
strongly associates with morbidity and mortality. The clinical benefits of a timely and …
strongly associates with morbidity and mortality. The clinical benefits of a timely and …
Biomarkers for the early detection of acute kidney injury
P Devarajan - Current opinion in pediatrics, 2011 - journals.lww.com
It is vital that additional large future studies demonstrate the association between biomarkers
and hard clinical outcomes independent of serum creatinine concentrations and that …
and hard clinical outcomes independent of serum creatinine concentrations and that …