Comparative accuracy of biomarkers for the prediction of hospital-acquired acute kidney injury: a systematic review and meta-analysis

HC Pan, SY Yang, TTY Chiou, CC Shiao, CH Wu… - Critical Care, 2022 - Springer
Background Several biomarkers have been proposed to predict the occurrence of acute
kidney injury (AKI); however, their efficacy varies between different trials. The aim of this …

The multifaceted roles of neutrophil gelatinase associated lipocalin (NGAL) in inflammation and cancer

S Chakraborty, S Kaur, S Guha, SK Batra - Biochimica et Biophysica Acta …, 2012 - Elsevier
Neutrophil gelatinase associated lipocalin (NGAL), also known as oncogene 24p3,
uterocalin, siderocalin or lipocalin 2, is a 24kDa secreted glycoprotein originally purified …

The outcome of neutrophil gelatinase-associated lipocalin-positive subclinical acute kidney injury: a multicenter pooled analysis of prospective studies

M Haase, P Devarajan, A Haase-Fielitz… - Journal of the American …, 2011 - jacc.org
Objectives: The aim of this study was to test the hypothesis that, without diagnostic changes
in serum creatinine, increased neutrophil gelatinase-associated lipocalin (NGAL) levels …

Urinary and serum biomarkers for the diagnosis of acute kidney injury: an in-depth review of the literature

J Vanmassenhove, R Vanholder… - Nephrology Dialysis …, 2013 - academic.oup.com
Background Acute kidney injury (AKI) remains associated with high morbidity and mortality,
despite progress in medical care. Although the RIFLE (Risk, Injury, Failure, Loss, End-Stage …

Neutrophil gelatinase-associated lipocalin as a biomarker of acute kidney injury: a critical evaluation of current status

A Haase-Fielitz, M Haase… - Annals of clinical …, 2014 - journals.sagepub.com
Background The early prediction of acute kidney injury (AKI) by current clinical and
laboratory methods remains inadequate. Neutrophil gelatinase-associated lipocalin (NGAL) …

The rise and fall of NGAL in acute kidney injury

J Mårtensson, R Bellomo - Blood purification, 2014 - karger.com
For many years, neutrophil gelatinase-associated lipocalin (NGAL) has been considered the
most promising biomarker of acute kidney injury (AKI). Commercial assays and point-of-care …

[HTML][HTML] Comparison of standard and accelerated initiation of renal replacement therapy in acute kidney injury

R Wald, NKJ Adhikari, OM Smith, MA Weir, K Pope… - Kidney international, 2015 - Elsevier
In patients with severe acute kidney injury (AKI) but no urgent indication for renal
replacement therapy (RRT), the optimal time to initiate RRT remains controversial. While …

Neutrophil gelatinase-associated lipocalin measured on clinical laboratory platforms for the prediction of acute kidney injury and the associated need for dialysis …

C Albert, A Zapf, M Haase, C Röver… - American Journal of …, 2020 - Elsevier
Rationale & Objective The usefulness of measures of neutrophil gelatinase-associated
lipocalin (NGAL) in urine or plasma obtained on clinical laboratory platforms for predicting …

Diagnosis of acute kidney injury using functional and injury biomarkers: workgroup statements from the tenth Acute Dialysis Quality Initiative Consensus Conference

PA McCullough, AD Shaw, M Haase… - ADQI consensus on AKI …, 2013 - karger.com
Acute kidney injury (AKI) commonly occurs in hospitalized patients and is independently and
strongly associates with morbidity and mortality. The clinical benefits of a timely and …

Biomarkers for the early detection of acute kidney injury

P Devarajan - Current opinion in pediatrics, 2011 - journals.lww.com
It is vital that additional large future studies demonstrate the association between biomarkers
and hard clinical outcomes independent of serum creatinine concentrations and that …