Polymorphonuclear neutrophils are the most numerous leucocytes present in human blood,
and function as crucial players in innate immune responses. Neutrophils are indispensable …

Inflammation is a key characteristic of kidney disease, but this immune response is two-
faced. In the acute phase of kidney injury, there is an activation of the immune cells to fight …

Long-term peritoneal dialysis causes morphologic and functional changes in the peritoneal
membrane. Although mesothelial-mesenchymal transition of peritoneal mesothelial cells is a …

Lay summary Peritoneal dialysis (PD) uses the peritoneal membrane for dialysis. The
peritoneal membrane is a thin layer of tissue that lines the abdomen. The lining is used as a …

Systemic lupus erythematosus (SLE) is a disease characterized by dysregulation and
hyperreactivity of the immune response at various levels, including hyperactivation of …

Peritoneal fibrosis is characterized by abnormal production of extracellular matrix proteins
leading to progressive thickening of the submesothelial compact zone of the peritoneal …

Peritoneal dialysis (PD) is an efficient renal replacement therapy for patients with end-stage
renal disease. Even if it ensures an outcome equivalent to hemodialysis and a better quality …

Peritoneal dialysis (PD) is a renal replacement therapy for patients with end-stage renal
disease that is equivalent to hemodialysis with respect to adequacy, mortality, and other …

Peritoneal dialysis is a form of renal replacement alternative to the hemodialysis. During this
treatment, the peritoneal membrane acts as a permeable barrier for exchange of solutes and …

Diabetic nephropathy (DN) is one of the most common complications of diabetes, and
currently the first end-stage renal disease worldwide. New strategies to treat DN using …