Cancer risks from arsenic in drinking water.

AH Smith, C Hopenhayn-Rich, MN Bates… - Environmental …, 1992 - ehp.niehs.nih.gov
Ingestion of arsenic, both from water supplies and medicinal preparations, is known to cause
skin cancer. The evidence assessed here indicates that arsenic can also cause liver, lung …

Arsenic exposure and the induction of human cancers

VD Martinez, EA Vucic, DD Becker-Santos… - Journal of …, 2011 - Wiley Online Library
Arsenic is a metalloid, that is, considered to be a human carcinogen. Millions of individuals
worldwide are chronically exposed through drinking water, with consequences ranging from …

Arsenic in drinking water

National Research Council, Life Studies… - 1999 - books.google.com
The US Environmental Protection Agency (EPA) has been considering a more stringent
regulation of arsenic in water. A significant reduction in the maximum contaminant level …

Mechanisms of action of arsenic trioxide

WH Miller Jr, HM Schipper, JS Lee, J Singer… - Cancer research, 2002 - AACR
Arsenic trioxide has shown substantial efficacy in treating both newly diagnosed and
relapsedpatients with acute promyelocytic leukemia (APL). As a single agent, it induces …

A global health problem caused by arsenic from natural sources

JC Ng, J Wang, A Shraim - Chemosphere, 2003 - Elsevier
Arsenic is a carcinogen to both humans and animals. Arsenicals have been associated with
cancers of the skin, lung, and bladder. Clinical manifestations of chronic arsenic poisoning …

Hormesis: the dose-response revolution

EJ Calabrese, LA Baldwin - Annual review of pharmacology …, 2003 - annualreviews.org
Hormesis, a dose-response relationship phenomenon characterized by low-dose
stimulation and high-dose inhibition, has been frequently observed in properly designed …

Arsenic exposure and cardiovascular disease: a systematic review of the epidemiologic evidence

A Navas-Acien, AR Sharrett… - American journal of …, 2005 - academic.oup.com
Arsenic exposure is a likely cause of blackfoot disease and a potential risk factor for
atherosclerosis. The authors performed a systematic review of the epidemiologic evidence …

History of the development of arsenic derivatives in cancer therapy

S Waxman, KC Anderson - The oncologist, 2001 - academic.oup.com
Arsenic is a natural substance that has been used medicinally for over 2,400 years. In the
19th century, it was the mainstay of the materia medica. A solution of potassium arsenite …

[PDF][PDF] Arsenic ingestion and internal cancers: a review

MN Bates, AH Smith… - American Journal of …, 1992 - researchgate.net
Inorganic arsenic was one of the first chemicals for which there was evidence of a
carcinogenic effect. As early as 1879, it was suggested that high rates of lung cancer in …

Drinking water arsenic contamination, skin lesions, and malignancies: a systematic review of the global evidence

MR Karagas, A Gossai, B Pierce, H Ahsan - Current environmental health …, 2015 - Springer
Skin lesions and cancer are known manifestations of chronic exposure to arsenic
contaminated drinking water. Epidemiologic data primarily comes from regions with …