While the modern framework of evolutionary development (evo-devo) has been decidedly
genetic, historic analyses have also considered the importance of mechanics in the …

Formation of branched organs requires sequential differentiation of stem cells. In this work,
we find that the conducting airways derived from SOX2+ progenitors in the murine lungs fail …

Single-cell Sequencing technology (scSeq) has revolutionized our understanding of
individual cells, uncovering unprecedented heterogeneity within tissues and cell …

Summary Hormone-receptor-positive (HR+) luminal cells largely mediate the response to
estrogen and progesterone during mammary gland morphogenesis. However, there …

Branching morphogenesis is a characteristic feature of many essential organs, such as the
lung and kidney, and most glands, and is the net result of two tissue behaviors: branch point …

Recent studies support a model in which the progeny of SOX9+ epithelial progenitors at the
distal tip of lung branches undergo cell allocation and differentiation sequentially along the …

Branching morphogenesis is a characteristic feature of many essential organs such as the
lung, kidney, and most glands, and the net result of two tissue behaviors: branch point …

Comprehensive systematic account of the development of the avian respiratory system,
specifically that of the domestic fowl, Gallus gallus variant domesticus, is presented. Factors …

Prenatal exposure to environmental hazards such as cadmium (Cd) and arsenic (As) can
severely impair fetal lung development, leading to lifelong adverse effects. As two of the …

Branching morphogenesis is an important process in sha** the arborized structures of
several organs. However, the driving force that directs this process from progenitor pools …