Benzylisoquinoline alkaloids (BIAs) are a structurally diverse group of plant specialized
metabolites with a long history of investigation. Although the ecophysiological functions of …

Opium poppy (Papaver somniferum) is one of the world's oldest medicinal plants and
remains the only commercial source for the narcotic analgesics morphine, codeine and semi …

Medicinal plants are a rich source of highly diverse specialized metabolites with important
pharmacological properties. Until recently, plant biologists were limited in their ability to …

Clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated9
(Cas9) endonuclease system is a powerful RNA-guided genome editing tool. CRISPR/Cas9 …

The pharmacological actions of benzylisoquinoline alkaloids are quite substantial, and have
recently attracted much attention. One of the principle benzylisoquinoline alkaloids has been …

For nearly eight millennia, opium poppy (Papaver somniferum) has been bred and cultivated
for therapeutic purposes. The medicinal properties of the plant are conferred by specialized …

Tetrahydropapaverine (THP) and papaverine are plant natural products with clinically
significant roles. THP is a precursor in the production of the drugs atracurium and …

Covering: up to June 2024 Benzylisoquinoline alkaloids (BIAs) represent a diverse class of
plant specialized metabolites derived from L-tyrosine, exhibiting significant pharmacological …

The gateway to morphine biosynthesis in opium poppy (Papaver somniferum) is the
stereochemical inversion of (S)-reticuline since the enzyme yielding the first committed …

Opium poppy (P apaver somniferum) is an important medicinal plant producing
benzylisoquinoline alkaloids (BIA). Micro RNA s (mi RNA s) are endogenous small RNA s …