Thrombus composition and efficacy of thrombolysis and thrombectomy in acute ischemic stroke

P Jolugbo, RAS Ariëns - Stroke, 2021 - Am Heart Assoc
Thrombi retrieved from patients with acute ischemic stroke are highly heterogeneous.
Recent data suggest that thrombus composition may impact on mechanical thrombectomy …

Correlation of imaging and histopathology of thrombi in acute ischemic stroke with etiology and outcome: a systematic review

W Brinjikji, S Duffy, A Burrows, W Hacke… - Journal of …, 2017 - jnis.bmj.com
Background and purpose Studying the imaging and histopathologic characteristics of
thrombi in ischemic stroke could provide insights into stroke etiology and ideal treatment …

Clot friction variation with fibrin content; implications for resistance to thrombectomy

GM Gunning, K McArdle, M Mirza, S Duffy… - Journal of …, 2018 - jnis.bmj.com
Background Despite significant advancements in the procedural efficacy of mechanical
thrombectomy in patients with ischemic stroke in recent years, there still remains a portion of …

Risk of distal embolization with stent retriever thrombectomy and ADAPT

JY Chueh, AS Puri, AK Wakhloo… - Journal of …, 2016 - jnis.bmj.com
Background There is a discrepancy in clinical outcomes and the achieved recanalization
rates with stent retrievers in the endovascular treatment of ischemic stroke. It is our …

Histopathologic analysis of retrieved thrombi associated with successful reperfusion after acute stroke thrombectomy

T Hashimoto, M Hayakawa, N Funatsu, H Yamagami… - Stroke, 2016 - Am Heart Assoc
Background and Purpose—Histopathologic evaluation of occlusive thrombi retrieved from
cerebral arteries using endovascular therapy is possible. We investigated the relationship …

Reduction in distal emboli with proximal flow control during mechanical thrombectomy: a quantitative in vitro study

JY Chueh, AL Kühn, AS Puri, SD Wilson, AK Wakhloo… - Stroke, 2013 - Am Heart Assoc
Background and Purpose—To evaluate the impact of proximal flow control on efficacy and
safety of mechanical thrombectomy in an in vitro middle cerebral artery occlusion. Methods …

Analyses of thrombi in acute ischemic stroke: a consensus statement on current knowledge and future directions

SF De Meyer, T Andersson, B Baxter… - … journal of stroke, 2017 - journals.sagepub.com
Limited data exist on clot composition and detailed characteristics of arterial thrombi
associated with large vessel occlusion in acute ischemic stroke. Advances in endovascular …

Per-pass analysis of thrombus composition in patients with acute ischemic stroke undergoing mechanical thrombectomy

S Duffy, R McCarthy, M Farrell, S Thomas, P Brennan… - Stroke, 2019 - Am Heart Assoc
Background and Purpose—Mechanical thrombectomy may involve multiple attempts to
retrieve the occluding thrombus. This study examined the composition of thrombus …

Density of thrombus on admission CT predicts revascularization efficacy in large vessel occlusion acute ischemic stroke

P Moftakhar, JD English, DL Cooke, WT Kim, C Stout… - Stroke, 2013 - Am Heart Assoc
Background and Purpose—Can lysability of large vessel thrombi in acute ischemic stroke be
predicted by measuring clot density on admission nonenhanced CT (NECT), postcontrast …

Mechanical characterization of thrombi retrieved with endovascular thrombectomy in patients with acute ischemic stroke

N Boodt, PRW Snouckaert van Schauburg, HM Hund… - Stroke, 2021 - Am Heart Assoc
Background and Purpose: Mechanical properties of thromboemboli play an important role in
the efficacy of endovascular thrombectomy (EVT) for acute ischemic stroke. However, very …