Congenital adrenal hyperplasia (CAH) is a group of autosomal recessive disorders affecting
cortisol biosynthesis. Reduced activity of an enzyme required for cortisol production leads to …

Adrenal insufficiency can arise from a primary adrenal disorder, secondary to
adrenocorticotropic hormone deficiency, or by suppression of adrenocorticotropic hormone …

Objective: This clinical practice guideline addresses the diagnosis and treatment of primary
adrenal insufficiency. Participants: The Task Force included a chair, selected by The Clinical …

Adrenal glucocorticoids are major modulators of multiple functions, including energy
metabolism, stress responses, immunity, and cognition. The endogenous secretion of …

Adrenal insufficiency (AI) is a condition characterized by an absolute or relative deficiency of
adrenal cortisol production. Primary AI (PAI) is rare and is caused by direct adrenal failure …

Pituitary apoplexy, a rare clinical syndrome secondary to abrupt hemorrhage or infarction,
complicates 2%–12% of pituitary adenomas, especially nonfunctioning tumors. Headache of …

Objective: Adrenal crisis (AC) is a life-threatening complication of adrenal insufficiency (AI),
which according to retrospective data represents a significant clinical complication. Here we …

Adrenal insufficiency continues to be a challenge for patients, their physicians, and
researchers. During the past decade, long-term studies have shown increased mortality and …

Context The normal cortisol response 30 or 60 minutes after cosyntropin (ACTH [1–24]) is
considered to be≥ 18 μg/dL (500 nmol/L). This threshold is based on older serum cortisol …

Primary aldosteronism (PA) represents the most common cause of secondary hypertension,
but little is known regarding its adrenal cellular origins. Recently, aldosterone-producing cell …