METTL1-mediated m7G modification of Arg-TCT tRNA drives oncogenic transformation
The emerging" epitranscriptomics" field is providing insights into the biological and
pathological roles of different RNA modifications. The RNA methyltransferase METTL1 …
pathological roles of different RNA modifications. The RNA methyltransferase METTL1 …
[HTML][HTML] Codon-based indices for modeling gene expression and transcript evolution
S Bahiri-Elitzur, T Tuller - Computational and Structural Biotechnology …, 2021 - Elsevier
Codon usage bias (CUB) refers to the phenomena that synonymous codons are used in
different frequencies in most genes and organisms. The general assumption is that codon …
different frequencies in most genes and organisms. The general assumption is that codon …
System-wide analysis of RNA and protein subcellular localization dynamics
Although the subcellular dynamics of RNA and proteins are key determinants of cell
homeostasis, their characterization is still challenging. Here we present an integrative …
homeostasis, their characterization is still challenging. Here we present an integrative …
High CO2 levels drive the TCA cycle backwards towards autotrophy
L Steffens, E Pettinato, TM Steiner, A Mall, S König… - Nature, 2021 - nature.com
It has recently been shown that in anaerobic microorganisms the tricarboxylic acid (TCA)
cycle, including the seemingly irreversible citrate synthase reaction, can be reversed and …
cycle, including the seemingly irreversible citrate synthase reaction, can be reversed and …
Estimating maximal microbial growth rates from cultures, metagenomes, and single cells via codon usage patterns
Maximal growth rate is a basic parameter of microbial lifestyle that varies over several orders
of magnitude, with doubling times ranging from a matter of minutes to multiple days. Growth …
of magnitude, with doubling times ranging from a matter of minutes to multiple days. Growth …
A "Silent" Polymorphism in the MDR1 Gene Changes Substrate Specificity
Synonymous single-nucleotide polymorphisms (SNPs) do not produce altered coding
sequences, and therefore they are not expected to change the function of the protein in …
sequences, and therefore they are not expected to change the function of the protein in …
The code of silence: widespread associations between synonymous codon biases and gene function
F Supek - Journal of molecular evolution, 2016 - Springer
Some mutations in gene coding regions exchange one synonymous codon for another, and
thus do not alter the amino acid sequence of the encoded protein. Even though they are …
thus do not alter the amino acid sequence of the encoded protein. Even though they are …
Comparative analysis of codon bias in the chloroplast genomes of theaceae species
Z Wang, Q Cai, Y Wang, M Li, C Wang, Z Wang… - Frontiers in …, 2022 - frontiersin.org
Theaceae species are dicotyledonous angiosperms with extremely high ornamental and
economic value. The chloroplast genome is traditionally used to study species evolution …
economic value. The chloroplast genome is traditionally used to study species evolution …