Ever since the pre-molecular era, the birth of new genes with novel functions has been
considered to be a major contributor to adaptive evolutionary innovation. Here, I review the …

Genome data have revealed great variation in the numbers of genes in different organisms,
which indicates that there is a fundamental process of genome evolution: the origin of new …

The field of molecular evolution has experienced explosive growth in recent years due to the
rapid accumulation of genetic sequence data, continuous improvements to computer …

De novo gene birth is the process by which new genes evolve from DNA sequences that
were ancestrally non-genic. De novo genes represent a subset of novel genes, and may be …

Differences between males and females in the optimal phenotype that is favoured by
selection can be resolved by the evolution of differential gene expression in the two sexes …

INTRODUCTION Control of mosquito vectors has historically proven to be an effective
means of eliminating malaria. Human malaria is transmitted only by mosquitoes in the genus …

During the course of evolution, genomes acquire novel genetic elements as sources of
functional and phenotypic diversity, including new genes that originated in recent evolution …

Gene copies that stem from the mRNAs of parental source genes have long been viewed as
evolutionary dead-ends with little biological relevance. Here we review a range of recent …

Determining the evolutionary forces responsible for the maintenance of gene duplicates is
key to understanding the processes leading to evolutionary adaptation and novelty. In his …

Genes are perpetually added to and deleted from genomes during evolution. Thus, it is
important to understand how new genes are formed and how they evolve to be critical …