The generation of islet-like endocrine clusters from human pluripotent stem cells (hPSCs)
has the potential to provide an unlimited source of insulin-producing β cells for the treatment …

Since human embryonic stem cells were first differentiated to beating cardiomyocytes a
decade ago, interest in their potential applications has increased exponentially. This has …

Type 1 diabetes mellitus (T1DM) is a growing global health concern that affects
approximately 8.5 million individuals worldwide. T1DM is characterized by an autoimmune …

Millions of people lose or damage their organs or tissues due to disease, birth defects, or
accidents each year. Stem cells, such as embryonic stem cells (ESCs), induced pluripotent …

Human pluripotent stem cells (hPSCs) provide powerful resources for application in
regenerative medicine and pharmaceutical development. In the past decade, various …

Engineered myocardial tissues can be used to elucidate fundamental features of myocardial
biology, develop organotypic in vitro model systems, and as engineered tissue constructs for …

Human pluripotent stem cells (hPSCs), including human embryonic stem cells and induced
pluripotent stem cells, are promising for numerous biomedical applications, such as cell …

Background The production of cardiomyocytes from human induced pluripotent stem cells
(hiPSC) holds great promise for patient-specific cardiotoxicity drug testing, disease …

Human pluripotent stem cells (hPSCs), including embryonic and induced pluripotent stem
cells, constitute an extremely attractive tool for cell therapy. However, flexible platforms for …

Recently, various approaches for controlling the embryonic stem (ES) cell microenvironment
have been developed for regulating cellular fate decisions. It has been reported that the …