Membrane lipids interact with proteins in a variety of ways, ranging from providing a stable
membrane environment for proteins to being embedded in to detailed roles in complicated …

Highlights•Advances in structural biology and integrative modelling yield (near)-atomic
resolution structures of complete viruses.•Computer simulations can now elucidate the …

Cholesterol has been shown to affect the extent of coronavirus binding and fusion to cellular
membranes. The severity of Covid-19 infection is also known to be correlated with lipid …

Hypothesis Unravelling the structural diversity of cellular membranes is a paramount
challenge in life sciences. In particular, lipid composition affects the membrane collective …

During replication of herpesviruses, capsids escape from the nucleus into the cytoplasm by
budding at the inner nuclear membrane. This unusual process is mediated by the viral …

Enveloped viruses such as the flaviviruses represent a significant burden to human health
around the world, with hundreds of millions of people each year affected by dengue alone …

We showcase the combination of experimental neutron scattering data and molecular
dynamics (MD) simulations for exemplary phospholipid membrane systems. Neutron and X …

Flaviviruses include important human pathogens such as Dengue, Zika, West Nile, Yellow
fever, Japanese encephalitis, and Tick-borne encephalitis viruses as well as some emerging …

Understanding viral peptide detection and partitioning and the subsequent host membrane
composition-based response is essential for gaining insights into the viral mechanism. Here …

Flaviviruses are simple enveloped viruses exhibiting complex structural and functional
heterogeneities. Decades of research have provided crucial basic insights, antiviral …