Transfusion transmitted infections in thalassaemics: need for reappraisal of blood screening strategy in India

V Shyamala - Transfusion medicine, 2014 - Wiley Online Library
The aim of the study was to assess the blood safety in India through prevalence in
thalassaemic population. Safety of the blood supply is a subject of great concern for all …

Combination of least absolute shrinkage and selection operator with Bayesian Regularization artificial neural network (LASSO-BR-ANN) for QSAR studies using …

Z Mozafari, MA Chamjangali, M Arashi - Chemometrics and Intelligent …, 2020 - Elsevier
A combination of least absolute shrinkage and selection operator (LASSO) with Bayesian
Regularization feed-forward artificial neural network (LASSO-BR-ANN) was used as a new …

Characterizing early drug resistance-related events using geometric ensembles from HIV protease dynamics

O Sheik Amamuddy, NT Bishop, Ö Tastan Bishop - Scientific Reports, 2018 - nature.com
The use of antiretrovirals (ARVs) has drastically improved the life quality and expectancy of
HIV patients since their introduction in health care. Several millions are still afflicted …

[HTML][HTML] Assessment of a computational approach to predict drug resistance mutations for HIV, HBV and SARS-CoV-2

D Patel, SK Ono, L Bassit, K Verma, F Amblard… - Molecules, 2022 - mdpi.com
Viral resistance is a worldwide problem mitigating the effectiveness of antiviral drugs.
Mutations in the drug-targeting proteins are the primary mechanism for the emergence of …

Machine learning to improve the effectiveness of ANRS in predicting HIV drug resistance

Y Singh - Healthcare informatics research, 2017 - synapse.koreamed.org
Objectives Human immunodeficiency virus infection and acquired immune deficiency
syndrome (HIV/AIDS) is one of the major burdens of disease in develo** countries, and …

Predicting, Diagnosing, and treating Acute and early HIV infection in a Public Sector Facility in Eswatini

B Kerschberger, A Aung, Q Mpala… - JAIDS Journal of …, 2021 - journals.lww.com
Background: The lack of acute and early HIV infection (AEHI) diagnosis and care contributes
to high HIV incidence in resource-limited settings. We aimed to assess the yield of AEHI …

Antiretroviral drug resistance among antiretroviral‐naïve and treatment experienced patients infected with HIV in Iran

K Baesi, M Ravanshad… - Journal of medical …, 2014 - Wiley Online Library
Resistance to antiretroviral therapy (ART) threatens the success of programs to reduce HIV
morbidity and mortality, particularly in countries with few treatment options. In the present …

RHIVDB: a freely accessible database of HIV amino acid sequences and clinical data of infected patients

O Tarasova, A Rudik, D Kireev, V Poroikov - Frontiers in genetics, 2021 - frontiersin.org
Human immunodeficiency virus (HIV) infection remains one of the most severe problems for
humanity, particularly due to the development of HIV resistance. To evaluate an association …

Primary HIV Drug Resistance among Recently Infected Cases of HIV in North‐West India

CK Chauhan, PVM Lakshmi, V Sagar… - AIDS Research and …, 2019 - Wiley Online Library
Background. Antiretroviral treatment may lead to the emergence of HIV drug resistance,
which can be transmitted. HIV primary drug resistance (PDR) is of great public health …

Prediction and molecular field view of drug resistance in HIV-1 protease mutants

B Wang, Y He, X Wen, Z ** - Scientific Reports, 2022 - nature.com
Conquering the mutational drug resistance is a great challenge in anti-HIV drug
development and therapy. Quantitatively predicting the mutational drug resistance in …