Serpins are a superfamily of proteins, whose membership is based on the presence of a
single common core domain consisting of three β-sheets and 8-9 R-helices, and with a set of …

Cell-mediated immunity in arthropods: Hematopoiesis, coagulation, melanization and
opsonization - ScienceDirect Skip to main contentSkip to article Elsevier logo Journals & Books …

Many innate immune mechanisms are conserved throughout the animal kingdom. Manduca
sexta, a widely used model for insect biochemical research, employs these mechanisms to …

We present a comprehensive alignment and phylogenetic analysis of the serpins, a
superfamily of proteins with known members in higher animals, nematodes, insects, plants …

Ovalbumin is a protein of unknown function found in large quantities in avian egg-white.
Surprisingly, ovalbumin belongs to the serpin family although it lacks any protease inhibitory …

Arthropod hemolymph contains proteins with serine proteinase inhibitory activity. These
inhibitors may exist in plasma or in hemocyte granules. Serine proteinase inhibitors from the …

Serpins are the largest known family of serine proteinase inhibitors and perform a variety of
physiological functions in arthropods. Herein, we review the field of serpins in arthropod …

Extracellular serine proteinase cascades have evolved in vertebrates and invertebrates to
mediate rapid, local reactions to physiological or pathological cues. In mammalian plasma, a …

Proteolytic enzymes are potentially hazardous to their protein environment, so that their
activity must be carefully controlled. Living organisms use protein inhibitors as a major tool …

Members of the serpin family of serine proteinase inhibitors play important roles in the
inflammatory, coagulation, fibrinolytic, and complement cascades. An inherent part of their …