Mechanisms of neuroplasticity linking early adversity to depression: developmental considerations

TC Ho, LS King - Translational psychiatry, 2021 - nature.com
Early exposure to psychosocial adversity is among the most potent predictors of depression.
Because depression commonly emerges prior to adulthood, we must consider the …

Allostatic load measurement: A systematic review of reviews, database inventory, and considerations for neighborhood research

S Beese, J Postma, JM Graves - International journal of environmental …, 2022 - mdpi.com
Background: Neighborhoods are critical to understanding how environments influence
health outcomes. Prolonged environmental stressors, such as a lack of green spaces and …

[HTML][HTML] Effects of the COVID-19 pandemic on mental health and brain maturation in adolescents: Implications for analyzing longitudinal data

IH Gotlib, JG Miller, LR Borchers, SM Coury… - … psychiatry global open …, 2023 - Elsevier
Background The COVID-19 pandemic has caused significant stress and disruption for young
people, likely leading to alterations in their mental health and neurodevelopment. In this …

An exploration of dimensions of early adversity and the development of functional brain network connectivity during adolescence: Implications for trajectories of …

R Chahal, JG Miller, JP Yuan, JL Buthmann… - Development and …, 2022 - cambridge.org
Different dimensions of adversity may affect mental health through distinct neurobiological
mechanisms, though current supporting evidence consists largely of cross-sectional …

Higher executive control network coherence buffers against puberty-related increases in internalizing symptoms during the COVID-19 pandemic

R Chahal, JS Kirshenbaum, JG Miller, TC Ho… - Biological psychiatry …, 2021 - Elsevier
Background Early pubertal maturation has been posited to be a biopsychosocial risk factor
for the onset of internalizing psychopathology in adolescence; further, early-maturing youths …

[HTML][HTML] Longitudinal changes in amygdala, hippocampus and cortisol development following early caregiving adversity

M VanTieghem, M Korom, J Flannery, T Choy… - Developmental …, 2021 - Elsevier
Although decades of research have shown associations between early caregiving adversity,
stress physiology and limbic brain volume (eg, amygdala, hippocampus), the developmental …

Early life stress, systemic inflammation, and neural correlates of implicit emotion regulation in adolescents

JP Yuan, TC Ho, SM Coury, R Chahal… - Brain, Behavior, and …, 2022 - Elsevier
Exposure to early life stress (ELS) increases the risk for develo** psychopathology;
however, the mechanisms underlying this association are not clear. In this study we …

Early life stress predicts depressive symptoms in adolescents during the COVID-19 pandemic: The mediating role of perceived stress

IH Gotlib, LR Borchers, R Chahal, AJ Gifuni… - Frontiers in …, 2021 - frontiersin.org
Background Exposure to early life stress (ELS) is alarmingly prevalent and has been linked
to the high rates of depression documented in adolescence. Researchers have theorized …

[HTML][HTML] Evaluating measures of allostatic load in adolescents: A systematic review

E Whelan, J O'Shea, E Hunt, S Dockray - Psychoneuroendocrinology, 2021 - Elsevier
Background Adolescents can experience heightened stress due to biopsychosocial
changes that occur during this developmental stage. The 'wear and tear'of the physiological …

Early life stress, frontoamygdala connectivity, and biological aging in adolescence: a longitudinal investigation

JG Miller, TC Ho, KL Humphreys, LS King… - Cerebral …, 2020 - academic.oup.com
Early life stress (ELS) may accelerate frontoamygdala development related to
socioemotional processing, serving as a potential source of resilience. Whether this circuit is …