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Precision medicine in human heart modeling: perspectives, challenges, and opportunities
Precision medicine is a new frontier in healthcare that uses scientific methods to customize
medical treatment to the individual genes, anatomy, physiology, and lifestyle of each person …
medical treatment to the individual genes, anatomy, physiology, and lifestyle of each person …
The cardiovascular system: mathematical modelling, numerical algorithms and clinical applications
Mathematical and numerical modelling of the cardiovascular system is a research topic that
has attracted remarkable interest from the mathematical community because of its intrinsic …
has attracted remarkable interest from the mathematical community because of its intrinsic …
[HTML][HTML] A comprehensive and biophysically detailed computational model of the whole human heart electromechanics
While ventricular electromechanics is extensively studied in both physiological and
pathological conditions, four-chamber heart models have only been addressed recently; …
pathological conditions, four-chamber heart models have only been addressed recently; …
Integrated heart—coupling multiscale and multiphysics models for the simulation of the cardiac function
Mathematical modeling of the human heart and its function can expand our understanding of
various cardiac diseases, which remain the most common cause of death in the developed …
various cardiac diseases, which remain the most common cause of death in the developed …
Multiphysics and multiscale modelling, data–model fusion and integration of organ physiology in the clinic: ventricular cardiac mechanics
With heart and cardiovascular diseases continually challenging healthcare systems
worldwide, translating basic research on cardiac (patho) physiology into clinical care is …
worldwide, translating basic research on cardiac (patho) physiology into clinical care is …
[HTML][HTML] A cardiac electromechanical model coupled with a lumped-parameter model for closed-loop blood circulation
We propose a novel mathematical and numerical model for cardiac electromechanics,
wherein biophysically detailed core models describe the different physical processes …
wherein biophysically detailed core models describe the different physical processes …
[КНИГА][B] Mathematical modelling of the human cardiovascular system: data, numerical approximation, clinical applications
Mathematical and numerical modelling of the human cardiovascular system has attracted
remarkable research interest due to its intrinsic mathematical difficulty and the increasing …
remarkable research interest due to its intrinsic mathematical difficulty and the increasing …
Patient-specific models of cardiac biomechanics
A Krishnamurthy, CT Villongco, J Chuang… - Journal of computational …, 2013 - Elsevier
Patient-specific models of cardiac function have the potential to improve diagnosis and
management of heart disease by integrating medical images with heterogeneous clinical …
management of heart disease by integrating medical images with heterogeneous clinical …
Patient-specific cardiovascular computational modeling: diversity of personalization and challenges
Patient-specific computer models have been developed representing a variety of aspects of
the cardiovascular system spanning the disciplines of electrophysiology, electromechanics …
the cardiovascular system spanning the disciplines of electrophysiology, electromechanics …
[HTML][HTML] 3D–0D closed-loop model for the simulation of cardiac biventricular electromechanics
Two crucial factors for accurate numerical simulations of cardiac electromechanics, which
are also essential to reproduce the synchronous activity of the heart, are:(i) accounting for …
are also essential to reproduce the synchronous activity of the heart, are:(i) accounting for …