MicroRNAs and complex diseases: from experimental results to computational models

X Chen, D **e, Q Zhao, ZH You - Briefings in bioinformatics, 2019‏ - academic.oup.com
Plenty of microRNAs (miRNAs) were discovered at a rapid pace in plants, green algae,
viruses and animals. As one of the most important components in the cell, miRNAs play a …

Anti-miRNA oligonucleotides: A comprehensive guide for design

JF Lima, L Cerqueira, C Figueiredo, C Oliveira… - RNA biology, 2018‏ - Taylor & Francis
MicroRNAs (miRNAs) are small, non-coding RNA molecules that regulate gene expression
post-transcriptionally. As a consequence of their function towards mRNA, miRNAs are …

Neural inductive matrix completion with graph convolutional networks for miRNA-disease association prediction

J Li, S Zhang, T Liu, C Ning, Z Zhang, W Zhou - Bioinformatics, 2020‏ - academic.oup.com
Motivation Predicting the association between microRNAs (miRNAs) and diseases plays an
import role in identifying human disease-related miRNAs. As identification of miRNA …

Predicting miRNA–disease association based on inductive matrix completion

X Chen, L Wang, J Qu, NN Guan, JQ Li - Bioinformatics, 2018‏ - academic.oup.com
Motivation It has been shown that microRNAs (miRNAs) play key roles in variety of
biological processes associated with human diseases. In Consideration of the cost and …

BNPMDA: bipartite network projection for MiRNA–disease association prediction

X Chen, D **e, L Wang, Q Zhao, ZH You, H Liu - Bioinformatics, 2018‏ - academic.oup.com
Motivation A large number of resources have been devoted to exploring the associations
between microRNAs (miRNAs) and diseases in the recent years. However, the experimental …

Semi-supervised learning for potential human microRNA-disease associations inference

X Chen, GY Yan - Scientific reports, 2014‏ - nature.com
MicroRNAs play critical role in the development and progression of various diseases.
Predicting potential miRNA-disease associations from vast amount of biological data is an …

Prediction of microRNAs Associated with Human Diseases Based on Weighted k Most Similar Neighbors

P Xuan, K Han, M Guo, Y Guo, J Li, J Ding, Y Liu… - PloS one, 2013‏ - journals.plos.org
Background The identification of human disease-related microRNAs (disease miRNAs) is
important for further investigating their involvement in the pathogenesis of diseases. More …

Adaptive boosting-based computational model for predicting potential miRNA-disease associations

Y Zhao, X Chen, J Yin - Bioinformatics, 2019‏ - academic.oup.com
Motivation Recent studies have shown that microRNAs (miRNAs) play a critical part in
several biological processes and dysregulation of miRNAs is related with numerous …

LRSSLMDA: Laplacian regularized sparse subspace learning for MiRNA-disease association prediction

X Chen, L Huang - PLoS computational biology, 2017‏ - journals.plos.org
Predicting novel microRNA (miRNA)-disease associations is clinically significant due to
miRNAs' potential roles of diagnostic biomarkers and therapeutic targets for various human …

RWRMDA: predicting novel human microRNA–disease associations

X Chen, MX Liu, GY Yan - Molecular BioSystems, 2012‏ - pubs.rsc.org
Recently, more and more research has shown that microRNAs (miRNAs) play critical roles
in the development and progression of various diseases, but it is not easy to predict potential …