Immunotherapy in colorectal cancer: current achievements and future perspective

A Fan, B Wang, X Wang, Y Nie, D Fan… - … Journal of Biological …, 2021 - pmc.ncbi.nlm.nih.gov
Following dramatic success in many types of advanced solid tumors, interest in
immunotherapy for the treatment of colorectal cancer (CRC) is increasingly growing. Given …

Detecting liquid remnants of solid tumors: circulating tumor DNA minimal residual disease

EJ Moding, BY Nabet, AA Alizadeh, M Diehn - Cancer discovery, 2021 - aacrjournals.org
Growing evidence demonstrates that circulating tumor DNA (ctDNA) minimal residual
disease (MRD) following treatment for solid tumors predicts relapse. These results suggest …

[HTML][HTML] Localised colon cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

G Argilés, J Tabernero, R Labianca, D Hochhauser… - Annals of …, 2020 - Elsevier
Colorectal cancer (CRC) is the third most common tumour in men and the second in women,
accounting for 10% of all tumour types worldwide. Incidence is 25% higher in males and …

5-fluorouracil and other fluoropyrimidines in colorectal cancer: Past, present and future

S Vodenkova, T Buchler, K Cervena… - Pharmacology & …, 2020 - Elsevier
Fluorouracil (5-FU) is an essential component of systemic chemotherapy for colorectal
cancer (CRC) in the palliative and adjuvant settings. Over the past four decades, several …

Incidence of recurrence and time to recurrence in stage I to III colorectal cancer: a nationwide Danish cohort study

J Nors, LH Iversen, R Erichsen, KA Gotschalck… - JAMA …, 2024 - jamanetwork.com
Importance Management of colorectal cancer (CRC) has been updated continuously over
the past 2 decades. While the combination of these initiatives has had implications for …

Immunotherapy in colorectal cancer: rationale, challenges and potential

K Ganesh, ZK Stadler, A Cercek… - Nature reviews …, 2019 - nature.com
Following initial successes in melanoma treatment, immunotherapy has rapidly become
established as a major treatment modality for multiple types of solid cancers, including a …

Pathological features and prognostication in colorectal cancer

K Chen, G Collins, H Wang, JWT Toh - Current Oncology, 2021 - mdpi.com
The prognostication of colorectal cancer (CRC) has traditionally relied on staging as defined
by the Union for International Cancer Control (UICC) and American Joint Committee on …

ctDNA applications and integration in colorectal cancer: an NCI Colon and Rectal–Anal Task Forces whitepaper

A Dasari, VK Morris, CJ Allegra, C Atreya… - Nature reviews Clinical …, 2020 - nature.com
An increasing number of studies are describing potential uses of circulating tumour DNA
(ctDNA) in the care of patients with colorectal cancer. Owing to this rapidly develo** area …

Global trends in colorectal cancer mortality: projections to the year 2035

M Araghi, I Soerjomataram, M Jenkins… - … journal of cancer, 2019 - Wiley Online Library
Colorectal cancer (CRC) is the third most common cancer worldwide and the fourth most
common cause of cancer death. Predictions of the future burden of the disease inform health …

Stage IV colorectal cancer management and treatment

O Hernandez Dominguez, S Yilmaz… - Journal of clinical …, 2023 - mdpi.com
(1) Background: Colorectal cancer (CRC) is the third most common cancer and the second
leading cause of cancer-related mortality worldwide. Up to 50% of patients with CRC …