Mitochondria are the key source of ATP that fuels cellular functions, and they are also central
in cellular signaling, cell division and apoptosis. Dysfunction of mitochondria has been …

Creatine (Cr) is a ubiquitous molecule that is synthesized mainly in the liver, kidneys, and
pancreas. Most of the Cr pool is found in tissues with high-energy demands. Cr enters target …

The field of mitochondrial ion channels has recently seen substantial progress, including the
molecular identification of some of the channels. An integrative approach using genetics …

Reducing infarct size during a cardiac ischaemic‐reperfusion episode is still of paramount
importance, because the extension of myocardial necrosis is an important risk factor for …

Mitochondrial dynamics is a recent topic of research in the field of cardiac physiology. The
study of mechanisms involved in the morphological changes and in the mobility of …

Background Muscle wasting and weakness in Duchenne muscular dystrophy (DMD) causes
severe locomotor limitations and early death due in part to respiratory muscle failure. Given …

A growing body of research is investigating the potential contribution of mitochondrial
function to the etiology of type 2 diabetes. Numerous in vitro, in situ, and in vivo …

Key points Following fish oil supplementation, omega‐3 fatty acids are incorporated into
cellular membranes, which may affect lipid–protein interactions and therefore the function of …

Muscle weakness and wasting are defining features of cancer-induced cachexia.
Mitochondrial stress occurs before atrophy in certain muscles, but the possibility of …

Simple Summary Chemotherapy resistance is a common occurrence during cancer
treatment that cancer researchers are attempting to understand and overcome. Mitochondria …