Physical forces are ubiquitous in biological processes across scales and diverse contexts.
This review highlights the significance of mechanical forces in nervous system development …

Electrical stimulation (ES), as one of the physical therapy modalities for tumors, has attracted
extensive attention of researchers due to its promising efficacy. With the continuous …

During embryogenesis tissue layers undergo morphogenetic flow rearranging and folding
into specific shapes. While developmental biology has identified key genes and local …

Mechanosensing is a ubiquitous process to translate external mechanical stimuli into
biological responses. Piezo1 ion channels are directly gated by mechanical forces and play …

Pathological angiogenesis frequently occurs in tumor tissue, limiting the efficiency of
chemotherapeutic drug delivery and accelerating tumor progression. However, traditional …

The contribution of endocardial cells (EdCs) to the hematopoietic lineages has been
strongly debated. Here, we provide evidence that in zebrafish, the endocardium gives rise to …

Nature offers a wealth of opportunities to solve scientific and technological issues based on
its unique structures and function. The dynamic non‐covalent interaction is considered to be …

Epithelial-to-mesenchymal transitions (EMTs) of both endocardium and epicardium guide
atrioventricular heart valve formation, but the cellular complexity and small scale of this …

Organ morphogenesis involves dynamic changes of tissue properties while cells adapt to
their mechanical environment through mechanosensitive pathways. How mechanical cues …

Excessive oxidative response, unbalanced immunomodulation, and impaired mesenchymal
stem cell function in periodontitis in diabetes makes it a great challenge to achieve …