Bile acids have received considerable interest in the drug delivery research due to their
peculiar physicochemical properties and biocompatibility. The main advantage of bile acids …

Bile acids are synthesized in the liver, stored in the gallbladder, and secreted into the
duodenum at meals. Apical sodium-dependent bile acid transporter (ASBT), an ileal Na+ …

Cationic and ionizable cationic lipids are broadly applied as auxiliary agents, but their use is
associated with adverse effects. If these excipients are rapidly degraded to endogenously …

In last few years, therapeutic peptides/proteins are rapidly growing in drug market
considering their higher efficiency and lower toxicity than chemical drugs. However, the …

Despite many ongoing and innovative approaches, there are still formidable challenges in
the clinical translation of oral peptide drugs into marketable products due to their low …

Abstract Aim Diabetic (type-2) is a metabolic disease characterized by increased blood
glucose level from the normal level. In the present study, apigenin (AG) loaded lipid vesicles …

Bile salts (BSs) are naturally occurring rigid surfactants with a steroidal skeleton and specific
self-assembly and interface behaviors. Using bile salts as precursors, derivatives can be …

Abstract Apical Sodium-dependent Bile Acid Transporter (ASBT) actively reabsorbs bile
acids (BAs) from the gut lumen. This process is a critical step in the enterohepatic circulation …

Convenient multiple dosing makes oral administration an ideal route for delivery of
therapeutic siRNA. However, hostile GI environments and nonspecific biological trafficking …

The development of highly funtional and orally available nanoparticles is the ultimate goal in
nanoparticle delivery. Various functional nanoparticles have been studied to that end but …