Panel data are observations of a continuous-time process at arbitrary times, for example,
visits to a hospital to diagnose disease status. Multi-state models for such data are generally …

Context The prognostic importance of local failure after definitive radiotherapy (RT) in
National Comprehensive Cancer Network intermediate-and high-risk prostate cancer (PCa) …

The rates and routes of lethal systemic spread in breast cancer are poorly understood owing
to a lack of molecularly characterized patient cohorts with long-term, detailed follow-up data …

This book serves as an introductory guide for students and analysts who need to work with
survival time data. The minimum prerequisites are basic applied courses in linear regression …

Abstract flexsurv is an R package for fully-parametric modeling of survival data. Any
parametric time-to-event distribution may be fitted if the user supplies a probability density or …

Purpose Outcome of childhood acute lymphoblastic leukemia (ALL) improved greatly by
intensifying chemotherapy for all patients. Minimal residual disease (MRD) levels during the …

Background: Hypertrophic cardiomyopathy is the leading cause of sudden cardiac death
(SCD) in children and young adults. Our objective was to develop and validate a SCD risk …

Background Although lifestyle factors have been studied in relation to individual non-
communicable diseases (NCDs), their association with development of a subsequent NCD …

This book covers competing risks and multistate models, sometimes summarized as event
history analysis. These models generalize the analysis of time to a single event (survival …

Background: The risk for and consequences of recurrent mitral regurgitation (MR) following
degenerative mitral valve repair are poorly understood. Objectives: This study sought to …