Role of the prefrontal cortex in pain processing

WY Ong, CS Stohler, DR Herr - Molecular neurobiology, 2019 - Springer
The prefrontal cortex (PFC) is not only important in executive functions, but also pain
processing. The latter is dependent on its connections to other areas of the cerebral …

Neuromodulators for functional gastrointestinal disorders (disorders of gut− brain interaction): a Rome foundation working team report

DA Drossman, J Tack, AC Ford, E Szigethy… - Gastroenterology, 2018 - Elsevier
Background & Aims Central neuromodulators (antidepressants, antipsychotics, and other
central nervous system− targeted medications) are increasingly used for treatment of …

Fibromyalgia syndrome: etiology, pathogenesis, diagnosis, and treatment

E Bellato, E Marini, F Castoldi… - Pain research and …, 2012 - Wiley Online Library
Fibromyalgia syndrome is mainly characterized by pain, fatigue, and sleep disruption. The
etiology of fibromyalgia is still unclear: if central sensitization is considered to be the main …

Brain changes associated with cognitive and emotional factors in chronic pain: a systematic review

A Malfliet, I Coppieters, P Van Wilgen… - … Journal of Pain, 2017 - Wiley Online Library
An emerging technique in chronic pain research is MRI, which has led to the understanding
that chronic pain patients display brain structure and function alterations. Many of these …

[HTML][HTML] Structural brain anomalies and chronic pain: a quantitative meta-analysis of gray matter volume

RF Smallwood, AR Laird, AE Ramage, AL Parkinson… - The Journal of …, 2013 - Elsevier
The diversity of chronic pain syndromes and the methods employed to study them make
integrating experimental findings challenging. This study performed coordinate-based meta …

One single diagnosis, bodily distress syndrome, succeeded to capture 10 diagnostic categories of functional somatic syndromes and somatoform disorders

P Fink, A Schröder - Journal of psychosomatic research, 2010 - Elsevier
BACKGROUND: In order to clarify the classification of physical complaints not attributable to
verifiable, conventionally defined diseases, a new diagnosis of bodily distress syndrome …

Pain imaging in health and disease—how far have we come?

P Schweinhardt, MC Bushnell - The Journal of clinical …, 2010 - Am Soc Clin Investig
Since modern brain imaging of pain began 20 years ago, networks in the brain related to
pain processing and those related to different types of pain modulation, including placebo …

[HTML][HTML] Structural alterations in functional neurological disorder and related conditions: a software and hardware problem?

I Bègue, C Adams, J Stone, DL Perez - NeuroImage: Clinical, 2019 - Elsevier
Functional neurological (conversion) disorder (FND) is a condition at the interface of
neurology and psychiatry. A “software” vs.“hardware” analogy describes abnormal …

The interruptive effect of pain on attention

DJ Moore, E Keogh… - Quarterly journal of …, 2012 - journals.sagepub.com
Pain is known to disrupt attentional performance in both healthy adults and patients with
chronic pain. Exactly which aspects of attentional function are affected are, however, still to …

[HTML][HTML] Gray matter alterations in chronic pain: a network-oriented meta-analytic approach

F Cauda, S Palermo, T Costa, R Torta, S Duca… - NeuroImage: Clinical, 2014 - Elsevier
Several studies have attempted to characterize morphological brain changes due to chronic
pain. Although it has repeatedly been suggested that longstanding pain induces gray matter …