In recent years, indolylglyoxylamide-based derivatives have received much attention due to
their application in drug design and discovery, leading to the development of a wide array of …

The cinnamyl piperazine motif is a crucial element in drugs targeting various biological
targets. Medicinal chemistry researchers have designed and synthesized drug-like cinnamyl …

In this study, a commercial agent with antivirus activity and moroxydine hydrochloride were
employed to perform a lead optimization. A series of 1, 3, 5-triazine derivatives with …

Abstract The viral NS2B-NS3 protease is a promising drug target to combat dengue virus
(DENV) and other emerging flaviviruses. The discovery of novel DENV protease inhibitors …

Mosquito-borne viruses (MBVs) are a major global health threat, causing significant
morbidity and mortality. MBVs belong to several distinct viral families, each with unique …

Dengue, a mosquito‐borne disease transmitted by Aedes mosquitoes, is a significant global
health concern. Despite extensive research, effective treatments remain limited. The indole …

MolPredictX is a free-access web tool in which it is possible to analyze the prediction of
biological activity of chemical molecules. MolPredictX has been available online to the …

Abstract The viral NS2B-NS3 protease is a promising drug development target to combat
dengue virus (DENV) and other emerging flaviviruses. 4-(Benzyloxy) phenylglycine …