Abstract The Human Reference Atlas (HRA) aims to map all of the cells of the human body
to advance biomedical research and clinical practice. This Perspective presents …

An increasing number of patients worldwide suffers from chronic kidney disease (CKD).
CKD is accompanied by kidney fibrosis, which affects all compartments of the kidney, ie, the …

Chronic kidney disease (CKD) and acute kidney injury (AKI) are common, heterogeneous,
and morbid diseases. Mechanistic characterization of CKD and AKI in patients may facilitate …

Kidney Precision Medicine Project (KPMP) is building a spatially specified human kidney
tissue atlas in health and disease with single-cell resolution. Here, we describe the …

In nephrology, differential diagnosis or assessment of disease activity largely relies on the
analysis of glomerular filtration rate, urinary sediment, proteinuria and tissue obtained …

Technological advances in both genome sequencing and prenatal imaging are increasing
our ability to accurately recognize and diagnose Mendelian conditions prenatally …

Background Image-based machine learning tools hold great promise for clinical applications
in pathology research. However, the ideal end-users of these computational tools (eg …

The search for molecular species that are differentially expressed between biological states
is an important step towards discovering promising biomarker candidates. In imaging mass …

Abstract Background Head and Neck Cancer (HNC) has a high incidence and prevalence in
the worldwide population. The broad terminology associated with these diseases and their …

Rationale & Objectives Artificial intelligence driven by machine learning algorithms is being
increasingly employed for early detection, disease diagnosis, and clinical management. We …