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A decade of CDK5
R Dhavan, LH Tsai - Nature reviews Molecular cell biology, 2001 - nature.com
Since it was identified a decade ago, cyclin-dependent kinase 5 (CDK5) has emerged as a
crucial regulator of neuronal migration in the develo** central nervous system. CDK5 …
crucial regulator of neuronal migration in the develo** central nervous system. CDK5 …
Cyclin-dependent kinases in brain development and disease
SC Su, LH Tsai - Annual review of cell and developmental …, 2011 - annualreviews.org
Cyclin-dependent kinase 5 (Cdk5) is a multifaceted serine/threonine kinase protein with
important roles in the nervous system. Two related proteins, p35 and p39, activate Cdk5 …
important roles in the nervous system. Two related proteins, p35 and p39, activate Cdk5 …
Cocaine-induced dendritic spine formation in D1 and D2 dopamine receptor-containing medium spiny neurons in nucleus accumbens
KW Lee, Y Kim, AM Kim, K Helmin, AC Nairn… - Proceedings of the …, 2006 - pnas.org
Psychostimulant-induced alteration of dendritic spines on dopaminoceptive neurons in
nucleus accumbens (NAcc) has been hypothesized as an adaptive neuronal response that …
nucleus accumbens (NAcc) has been hypothesized as an adaptive neuronal response that …
Nuclear import impairment causes cytoplasmic trans-activation response DNA-binding protein accumulation and is associated with frontotemporal lobar degeneration
Trans-activation response DNA-binding protein (TDP-43) accumulation is the major
component of ubiquitinated protein inclusions found in patients with amyotrophic lateral …
component of ubiquitinated protein inclusions found in patients with amyotrophic lateral …
Serine 732 phosphorylation of FAK by Cdk5 is important for microtubule organization, nuclear movement, and neuronal migration
The serine/threonine kinase Cdk5 plays an essential role in neuronal positioning during
corticogenesis, but the underlying mechanisms are unknown. In nonneuronal cells, the …
corticogenesis, but the underlying mechanisms are unknown. In nonneuronal cells, the …
[HTML][HTML] Wnt/β-catenin signaling in dermal condensates is required for hair follicle formation
Broad dermal Wnt signaling is required for patterned induction of hair follicle placodes and
subsequent Wnt signaling in placode stem cells is essential for induction of dermal …
subsequent Wnt signaling in placode stem cells is essential for induction of dermal …
Transcriptional regulation of β-secretase by p25/cdk5 leads to enhanced amyloidogenic processing
Summary Cyclin-dependent kinase 5 (cdk5) has been implicated in Alzheimer's disease
(AD) pathogenesis. Here, we demonstrate that overexpression of p25, an activator of cdk5 …
(AD) pathogenesis. Here, we demonstrate that overexpression of p25, an activator of cdk5 …
Synaptic plasticity and cell cycle activation in neurons are alternative effector pathways: the 'Dr. Jekyll and Mr. Hyde concept'of Alzheimer's disease or the yin and yang …
T Arendt - Progress in neurobiology, 2003 - Elsevier
Mental actions are based on the dynamic organization of neuronal networks. In particular,
phylogenetically young brain areas (eg, cortical associative circuits) involved in the …
phylogenetically young brain areas (eg, cortical associative circuits) involved in the …
Cyclin-dependent kinase 5 activity controls cell motility and metastatic potential of prostate cancer cells
We show here that cyclin-dependent kinase 5 (CDK5), a known regulator of migration in
neuronal development, plays an important role in prostate cancer motility and metastasis …
neuronal development, plays an important role in prostate cancer motility and metastasis …
Cables links Robo-bound Abl kinase to N-cadherin-bound β-catenin to mediate Slit-induced modulation of adhesion and transcription
J Rhee, T Buchan, L Zukerberg, J Lilien… - Nature cell biology, 2007 - nature.com
Binding of the secreted axon guidance cue Slit to its Robo receptor results in inactivation of
the neural, calcium-dependent cell–cell adhesion molecule N-cadherin, providing a rapid …
the neural, calcium-dependent cell–cell adhesion molecule N-cadherin, providing a rapid …