Recent advances in single-molecule tracking and imaging techniques
Since the early 1990s, single-molecule detection in solution at room temperature has
enabled direct observation of single biomolecules at work in real time and under …
enabled direct observation of single biomolecules at work in real time and under …
Single-particle diffusional fingerprinting: A machine-learning framework for quantitative analysis of heterogeneous diffusion
Single-particle tracking (SPT) is a key tool for quantitative analysis of dynamic biological
processes and has provided unprecedented insights into a wide range of systems such as …
processes and has provided unprecedented insights into a wide range of systems such as …
Classification of diffusion modes in single-particle tracking data: Feature-based versus deep-learning approach
Single-particle trajectories measured in microscopy experiments contain important
information about dynamic processes occurring in a range of materials including living cells …
information about dynamic processes occurring in a range of materials including living cells …
The decade of super-resolution microscopy of the presynapse
G Nosov, M Kahms, J Klingauf - Frontiers in synaptic neuroscience, 2020 - frontiersin.org
The presynaptic compartment of the chemical synapse is a small, yet extremely complex
structure. Considering its size, most methods of optical microscopy are not able to resolve its …
structure. Considering its size, most methods of optical microscopy are not able to resolve its …
Classification of particle trajectories in living cells: Machine learning versus statistical testing hypothesis for fractional anomalous diffusion
Single-particle tracking (SPT) has become a popular tool to study the intracellular transport
of molecules in living cells. Inferring the character of their dynamics is important, because it …
of molecules in living cells. Inferring the character of their dynamics is important, because it …
Quantitative evaluation of methods to analyze motion changes in single-particle experiments
The analysis of live-cell single-molecule imaging experiments can reveal valuable
information about the heterogeneity of transport processes and interactions between cell …
information about the heterogeneity of transport processes and interactions between cell …
Anomalous subdiffusion in living cells: Bridging the gap between experiments and realistic models through collaborative challenges
The life of a cell is governed by highly dynamical microscopic processes. Two notable
examples are the diffusion of membrane receptors and the kinetics of transcription factors …
examples are the diffusion of membrane receptors and the kinetics of transcription factors …
Learning physical properties of anomalous random walks using graph neural networks
Single particle tracking allows probing how biomolecules interact physically with their
natural environments. A fundamental challenge when analysing recorded single particle …
natural environments. A fundamental challenge when analysing recorded single particle …
“Waltz” of Cell Membrane-Coated Nanoparticles on Lipid Bilayers: Tracking Single Particle Rotation in Ligand–Receptor Binding
Understanding the binding of nanoparticles to receptors on biomembranes is critical to the
development and screening of therapeutic materials. A prevailing understanding is that …
development and screening of therapeutic materials. A prevailing understanding is that …
Interferometric scattering (iSCAT) microscopy and related techniques
Interferometric scattering (iSCAT) microscopy is a powerful tool for label-free sensitive
detection and imaging of nanoparticles to high spatiotemporal resolution. As it was born out …
detection and imaging of nanoparticles to high spatiotemporal resolution. As it was born out …