Microvascular dysfunction in diabetes mellitus and cardiometabolic disease

WB Horton, EJ Barrett - Endocrine reviews, 2021 - academic.oup.com
This review takes an inclusive approach to microvascular dysfunction in diabetes mellitus
and cardiometabolic disease. In virtually every organ, dynamic interactions between the …

Optical coherence tomography (angiography) biomarkers in the assessment and monitoring of diabetic macular edema

CI Suciu, VI Suciu, SD Nicoara - Journal of Diabetes Research, 2020 - Wiley Online Library
Retinopathy is one of the most severe diabetes‐related complications, and macular edema
is the major cause of central vision loss in patients with diabetes mellitus. Significant …

Porcine models for studying complications and organ crosstalk in diabetes mellitus

S Renner, A Blutke, S Clauss, CA Deeg, E Kemter… - Cell and tissue …, 2020 - Springer
The worldwide prevalence of diabetes mellitus and obesity is rapidly increasing not only in
adults but also in children and adolescents. Diabetes is associated with macrovascular …

Perspectives of diabetic retinopathy—challenges and opportunities

S Sivaprasad, S Sen, J Cunha-Vaz - Eye, 2023 - nature.com
Diabetic retinopathy (DR) may lead to vision-threatening complications in people living with
diabetes mellitus. Decades of research have contributed to our understanding of the …

[HTML][HTML] Standardization of optical coherence tomography angiography imaging biomarkers in diabetic retinal disease

S Vujosevic, J Cunha-Vaz, J Figueira… - Ophthalmic …, 2021 - karger.com
Optical coherence tomography Angiography (OCT-A) represents a revolution in the
noninvasive evaluation of retinal and choroidal circulation especially in detecting early …

Unmet needs in ophthalmology: a European Vision Institute-consensus roadmap 2019–2025

C Cursiefen, F Cordeiro, J Cunha-Vaz… - Ophthalmic …, 2019 - karger.com
Purpose: To define unmet needs in ophthalmology that can realistically be addressed in the
next 5 years (2019–2025) and describe potential avenues for research to address these …

[HTML][HTML] Associations between peripapillary retinal nerve fiber layer and choroidal thickness with the development and progression of diabetic retinopathy

X Gong, W Wang, K **ong, L Wang… - … & Visual Science, 2022 - iovs.arvojournals.org
Purpose: To evaluate the role of the peripapillary retinal nerve fiber layer (pRNFL) and
peripapillary choroidal thickness (pCT) in the development and progression of diabetic …

Swept-source OCTA quantification of capillary closure predicts ETDRS severity staging of NPDR

T Santos, LH Warren, AR Santos, IP Marques… - British Journal of …, 2022 - bjo.bmj.com
Purpose To test whether a single or composite set of parameters evaluated with optical
coherence tomography angiography (OCTA), representing retinal capillary closure, can …

Correlation between choroidal vascularity index and outer retina in patients with diabetic retinopathy

P Sidorczuk, I Obuchowska, J Konopinska… - Journal of clinical …, 2022 - mdpi.com
The choroid supplies blood to the outer retina. We quantified outer retinal and choroidal
parameters to understand better the pathogenesis of diabetic retinopathy (DR) and diabetic …

Comparison of different metrics for the identification of vascular changes in diabetic retinopathy using OCTA

L Mendes, IP Marques, J Cunha-Vaz - Frontiers in Neuroscience, 2021 - frontiersin.org
Retinal vessel metrics identifying microvascular changes such as vessel closure (VC) have
shown potential clinical value by identifying eyes with diabetic retinopathy (DR) at different …