Natural products for drug discovery in the 21st century: innovations for novel drug discovery

NE Thomford, DA Senthebane, A Rowe… - International journal of …, 2018 - mdpi.com
The therapeutic properties of plants have been recognised since time immemorial. Many
pathological conditions have been treated using plant-derived medicines. These medicines …

Underlying mechanisms of synergistic antioxidant interactions during lipid oxidation

I Bayram, EA Decker - Trends in food science & technology, 2023 - Elsevier
Background Unsaturated lipids undergo radical-initiated oxidative deterioration during lipid
oxidation, which is one of the most significant food quality and waste issues. Lipid oxidation …

Antioxidant activity/capacity measurement. 1. Classification, physicochemical principles, mechanisms, and electron transfer (ET)-based assays

R Apak, M Özyürek, K Güçlü… - Journal of agricultural …, 2016 - ACS Publications
Because there is no widely adopted “total antioxidant parameter” as a nutritional index for
labeling food and biological fluids, it is desirable to establish and standardize methods that …

Metabolomics in the context of plant natural products research: From sample preparation to metabolite analysis

MA Salem, L Perez de Souza, A Serag, AR Fernie… - Metabolites, 2020 - mdpi.com
Plant-derived natural products have long been considered a valuable source of lead
compounds for drug development. Natural extracts are usually composed of hundreds to …

The potential use of plant natural products and plant extracts with antioxidant properties for the prevention/treatment of neurodegenerative diseases: in vitro, in vivo …

F Pohl, P Kong Thoo Lin - Molecules, 2018 - mdpi.com
Neurodegenerative disorders, including Alzheimer's disease, Parkinson's disease and
Huntington's disease, present a major health issue and financial burden for health care …

Investigation of antioxidant synergisms and antagonisms among phenolic acids in the model matrices using FRAP and ORAC methods

D Skroza, V Šimat, L Vrdoljak, N Jolić, A Skelin… - Antioxidants, 2022 - mdpi.com
The total antioxidant potential of a sample cannot be predicted from the antioxidant activity of
its compounds; thus, scientists usually explain the overall activity through their combined …

Synergistic, antagonistic and additive antioxidant effects in the binary mixtures

M Olszowy-Tomczyk - Phytochemistry Reviews, 2020 - Springer
Food which is consumed by living organisms contains many antioxidants often with different
antioxidant abilities. In the case of antioxidants mixture its potential is not always an additive …

The synergistic and antagonistic antioxidant interactions of dietary phytochemical combinations

X Chen, H Li, B Zhang, Z Deng - Critical reviews in food science …, 2022 - Taylor & Francis
The frequent intake of whole foods and dietary food variety is recommended due to their
health benefits, such as prevention of multiple chronic diseases, including cancer …

Nanoemulsion-based basil seed gum edible film containing resveratrol and clove essential oil: In vitro antioxidant properties and its effect on oxidative stability and …

E Ansarian, M Aminzare, HH Azar, MR Mehrasbi… - Meat science, 2022 - Elsevier
The initial purpose of this study was to compare the in vitro antioxidant interactions between
resveratrol (RES) and clove essential oil (CEO) in conventional and nanoemulsion-based …

Pharmacological basis and new insights of resveratrol action in the cardiovascular system

CK Cheng, JY Luo, CW Lau, ZY Chen… - British Journal of …, 2020 - Wiley Online Library
Resveratrol (trans‐3, 4′, 5‐trihydroxystilbene) belongs to the family of natural phytoalexins.
Resveratrol first came to our attention in 1992, following reports of the cardioprotective …