Calcium signaling in astrocytes and gliotransmitter release

J Goenaga, A Araque, P Kofuji… - Frontiers in synaptic …, 2023 - frontiersin.org
Glia are as numerous in the brain as neurons and widely known to serve supportive roles
such as structural scaffolding, extracellular ionic and neurotransmitter homeostasis, and …

Astrocyte function from information processing to cognition and cognitive impairment

M Santello, N Toni, A Volterra - Nature neuroscience, 2019 - nature.com
Astrocytes serve important roles that affect recruitment and function of neurons at the local
and network levels. Here we review the contributions of astrocyte signaling to synaptic …

Physiology of astroglia

A Verkhratsky, M Nedergaard - Physiological reviews, 2018 - journals.physiology.org
Astrocytes are neural cells of ectodermal, neuroepithelial origin that provide for homeostasis
and defense of the central nervous system (CNS). Astrocytes are highly heterogeneous in …

The impact of studying brain plasticity

P Mateos-Aparicio… - Frontiers in cellular …, 2019 - frontiersin.org
Neural plasticity, also known as neuroplasticity or brain plasticity, can be defined as the
ability of the nervous system to change its activity in response to intrinsic or extrinsic stimuli …

[HTML][HTML] Astrocytic activation generates de novo neuronal potentiation and memory enhancement

A Adamsky, A Kol, T Kreisel, A Doron… - Cell, 2018 - cell.com
Astrocytes respond to neuronal activity and were shown to be necessary for plasticity and
memory. To test whether astrocytic activity is also sufficient to generate synaptic potentiation …

[HTML][HTML] Dopamine-evoked synaptic regulation in the nucleus accumbens requires astrocyte activity

M Corkrum, A Covelo, J Lines, L Bellocchio… - Neuron, 2020 - cell.com
Dopamine is involved in physiological processes like learning and memory, motor control
and reward, and pathological conditions such as Parkinson's disease and addiction. In …

Astrocyte calcium signaling: the third wave

N Bazargani, D Attwell - Nature neuroscience, 2016 - nature.com
The discovery that transient elevations of calcium concentration occur in astrocytes, and
release'gliotransmitters' which act on neurons and vascular smooth muscle, led to the idea …

Diversity of astrocyte functions and phenotypes in neural circuits

BS Khakh, MV Sofroniew - Nature neuroscience, 2015 - nature.com
Astrocytes tile the entire CNS. They are vital for neural circuit function, but have traditionally
been viewed as simple, homogenous cells that serve the same essential supportive roles …

Timing to be precise? An overview of spike timing-dependent plasticity, brain rhythmicity, and glial cells interplay within neuronal circuits

Y Andrade-Talavera, A Fisahn… - Molecular …, 2023 - nature.com
In the mammalian brain information processing and storage rely on the complex coding and
decoding events performed by neuronal networks. These actions are based on the …

Diversity and specificity of astrocyte–neuron communication

CA Durkee, A Araque - Neuroscience, 2019 - Elsevier
Astrocytes are emerging as important players in synaptic function, and, consequently, on
brain function and animal behavior. According to the Tripartite Synapse concept, astrocytes …