COVID‐19 is the disease evoked by a new breed of coronavirus called the severe acute
respiratory syndrome coronavirus 2 (SARS‐CoV‐2). Recently, COVID‐19 has become a …

The potential of the diverse chemistries present in natural products (NP) for biotechnology
and medicine remains untapped because NP databases are not searchable with raw data …

Deep-learning language models have shown promise in various biotechnological
applications, including protein design and engineering. Here we describe ProGen, a …

There has been an exponential increase in the design of synthetic antimicrobial peptides
(AMPs) for its use as novel antibiotics. Synthetic AMPs are substantially enriched in residues …

Most methods for single-cell transcriptome sequencing amplify the termini of polyadenylated
transcripts, capturing only a small fraction of the total cellular transcriptome. This precludes …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can cause acute
respiratory disease and multiorgan failure. Finding human host factors that are essential for …

INTRODUCTION Blood is the predominant source for molecular analyses in humans, both in
clinical and research settings, and is the target for many therapeutic strategies, emphasizing …

Generative modeling for protein engineering is key to solving fundamental problems in
synthetic biology, medicine, and material science. We pose protein engineering as an …

Metagenomic datasets contain billions of protein sequences that could greatly enhance
large-scale functional annotation and structure prediction. Utilizing this enormous resource …

Genomics, epigenomics, transcriptomics, proteomics and metabolomics efforts rapidly
generate a plethora of data on the activity and levels of biomolecules within mammalian …