Mitochondrial dysfunction and skeletal muscle atrophy: Causes, mechanisms, and treatment strategies
Skeletal muscle, which accounts for approximately 40% of total body weight, is one of the
most dynamic and plastic tissues in the human body and plays a vital role in movement …
most dynamic and plastic tissues in the human body and plays a vital role in movement …
Mitochondrial transplantation strategies in multifaceted induction of cancer cell death
Otto Warburg hypothesized that some cancer cells reprogram their metabolism, favoring
glucose metabolism by anaerobic glycolysis (Warburg effect) instead of oxidative …
glucose metabolism by anaerobic glycolysis (Warburg effect) instead of oxidative …
Mitochondrial transplantation ameliorates hippocampal damage following status epilepticus
X Jia, Q Wang, J Ji, W Lu, Z Liu, H Tian… - Animal Models and …, 2023 - Wiley Online Library
Background Hippocampal damage caused by status epilepticus (SE) can bring about
cognitive decline and emotional disorders, which are common clinical comorbidities in …
cognitive decline and emotional disorders, which are common clinical comorbidities in …
Mitochondrial transfer in tunneling nanotubes—a new target for cancer therapy
F Guan, X Wu, J Zhou, Y Lin, Y He, C Fan… - Journal of Experimental …, 2024 - Springer
A century ago, the Warburg effect was first proposed, revealing that cancer cells
predominantly rely on glycolysis during the process of tumorigenesis, even in the presence …
predominantly rely on glycolysis during the process of tumorigenesis, even in the presence …
The research progress of mitochondrial transplantation in the treatment of mitochondrial defective diseases
C Hu, Z Shi, X Liu, C Sun - International Journal of Molecular Sciences, 2024 - mdpi.com
Mitochondria are double-membrane organelles that are involved in energy production,
apoptosis, and signaling in eukaryotic cells. Several studies conducted over the past …
apoptosis, and signaling in eukaryotic cells. Several studies conducted over the past …
The role of mitochondria in iron overload-induced damage
Y Zhao, M Yang, X Liang - Journal of Translational Medicine, 2024 - Springer
Iron overload is a pathological condition characterized by the abnormal accumulation of iron
within the body, which may result from excessive iron intake, disorders of iron metabolism, or …
within the body, which may result from excessive iron intake, disorders of iron metabolism, or …
Clinical research framework proposal for ketogenic metabolic therapy in glioblastoma
Glioblastoma (GBM) is the most aggressive primary brain tumor in adults, with a universally
lethal prognosis despite maximal standard therapies. Here, we present a consensus …
lethal prognosis despite maximal standard therapies. Here, we present a consensus …
Metabolic reprogramming via mitochondrial delivery for enhanced maturation of chemically induced cardiomyocyte‐like cells
Y Nam, Y Song, SJ Seo, GR Ko, SH Lee, E Cha… - MedComm, 2024 - Wiley Online Library
Heart degenerative diseases pose a significant challenge due to the limited ability of native
heart to restore lost cardiomyocytes. Direct cellular reprogramming technology, particularly …
heart to restore lost cardiomyocytes. Direct cellular reprogramming technology, particularly …
The role of citrate synthase HbCS4 in latex regeneration of Hevea brasiliensis (para rubber tree)
Y Qin, J Yang, Z Wang, Y Fang, B Hu, X **ao… - Industrial Crops and …, 2023 - Elsevier
The rubber tree, Hevea brasiliensis, is a tropical rubber-yielding crop with economic
importance and provides over 90% of natural rubber (NR) for the global rubber industry. NR …
importance and provides over 90% of natural rubber (NR) for the global rubber industry. NR …
[HTML][HTML] The role of mitochondria transfer in cancer biological behavior, the immune system and therapeutic resistance
X Lyu, Y Yu, Y Jiang, Z Li, Q Qiao - Journal of Pharmaceutical Analysis, 2024 - Elsevier
Mitochondria play a crucial role as organelles, managing several physiological processes
such as redox balance, cell metabolism, and energy synthesis. Initially, the assumption was …
such as redox balance, cell metabolism, and energy synthesis. Initially, the assumption was …