Mitochondrial dysfunction and skeletal muscle atrophy: Causes, mechanisms, and treatment strategies

GB Kubat, E Bouhamida, O Ulger, I Turkel, G Pedriali… - Mitochondrion, 2023 - Elsevier
Skeletal muscle, which accounts for approximately 40% of total body weight, is one of the
most dynamic and plastic tissues in the human body and plays a vital role in movement …

Mitochondrial transplantation strategies in multifaceted induction of cancer cell death

A Cruz-Gregorio, AK Aranda-Rivera, I Amador-Martinez… - Life Sciences, 2023 - Elsevier
Otto Warburg hypothesized that some cancer cells reprogram their metabolism, favoring
glucose metabolism by anaerobic glycolysis (Warburg effect) instead of oxidative …

Mitochondrial transplantation ameliorates hippocampal damage following status epilepticus

X Jia, Q Wang, J Ji, W Lu, Z Liu, H Tian… - Animal Models and …, 2023 - Wiley Online Library
Background Hippocampal damage caused by status epilepticus (SE) can bring about
cognitive decline and emotional disorders, which are common clinical comorbidities in …

Mitochondrial transfer in tunneling nanotubes—a new target for cancer therapy

F Guan, X Wu, J Zhou, Y Lin, Y He, C Fan… - Journal of Experimental …, 2024 - Springer
A century ago, the Warburg effect was first proposed, revealing that cancer cells
predominantly rely on glycolysis during the process of tumorigenesis, even in the presence …

The research progress of mitochondrial transplantation in the treatment of mitochondrial defective diseases

C Hu, Z Shi, X Liu, C Sun - International Journal of Molecular Sciences, 2024 - mdpi.com
Mitochondria are double-membrane organelles that are involved in energy production,
apoptosis, and signaling in eukaryotic cells. Several studies conducted over the past …

The role of mitochondria in iron overload-induced damage

Y Zhao, M Yang, X Liang - Journal of Translational Medicine, 2024 - Springer
Iron overload is a pathological condition characterized by the abnormal accumulation of iron
within the body, which may result from excessive iron intake, disorders of iron metabolism, or …

Clinical research framework proposal for ketogenic metabolic therapy in glioblastoma

T Duraj, M Kalamian, G Zuccoli, JC Maroon… - BMC medicine, 2024 - Springer
Glioblastoma (GBM) is the most aggressive primary brain tumor in adults, with a universally
lethal prognosis despite maximal standard therapies. Here, we present a consensus …

Metabolic reprogramming via mitochondrial delivery for enhanced maturation of chemically induced cardiomyocyte‐like cells

Y Nam, Y Song, SJ Seo, GR Ko, SH Lee, E Cha… - MedComm, 2024 - Wiley Online Library
Heart degenerative diseases pose a significant challenge due to the limited ability of native
heart to restore lost cardiomyocytes. Direct cellular reprogramming technology, particularly …

The role of citrate synthase HbCS4 in latex regeneration of Hevea brasiliensis (para rubber tree)

Y Qin, J Yang, Z Wang, Y Fang, B Hu, X **ao… - Industrial Crops and …, 2023 - Elsevier
The rubber tree, Hevea brasiliensis, is a tropical rubber-yielding crop with economic
importance and provides over 90% of natural rubber (NR) for the global rubber industry. NR …

[HTML][HTML] The role of mitochondria transfer in cancer biological behavior, the immune system and therapeutic resistance

X Lyu, Y Yu, Y Jiang, Z Li, Q Qiao - Journal of Pharmaceutical Analysis, 2024 - Elsevier
Mitochondria play a crucial role as organelles, managing several physiological processes
such as redox balance, cell metabolism, and energy synthesis. Initially, the assumption was …