The unprecedented public health and economic impact of the COVID-19 pandemic caused
by infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been …

The lungs are constantly exposed to inhaled debris, allergens, pollutants, commensal or
pathogenic microorganisms, and respiratory viruses. As a result, innate and adaptive …

The global spread of SARS-CoV-2/COVID-19 is devastating health systems and economies
worldwide. Recombinant or vaccine-induced neutralizing antibodies are used to combat the …

A critical component in the interpretation of systems-level studies is the inference of enriched
biological pathways and protein complexes contained within OMICs datasets. Successful …

Human coronaviruses (CoVs) are enveloped viruses with a positive-sense single-stranded
RNA genome. Currently, six human CoVs have been reported including human coronavirus …

Influenza A viruses (IAVs) are contagious pathogens responsible for severe respiratory
infection in humans and animals worldwide. Upon detection of IAV infection, host immune …

Interferon-induced transmembrane proteins (IFITMs) are broad spectrum antiviral factors that
inhibit the entry of a wide range of clinically important pathogens including influenza A virus …

Virus entry, consisting of attachment to and penetration into the host target cell, is the first
step of the virus life cycle and is a critical 'do or die'event that governs virus emergence in …

A deficient interferon (IFN) response to severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) infection has been implicated as a determinant of severe coronavirus …

Cumulative data link cytokine storms with coronavirus disease 2019 (COVID-19) severity.
The precise identification of immune cell subsets in bronchoalveolar lavage (BAL) and their …