Taurine is a naturally occurring sulfur-containing amino acid that is found abundantly in
excitatory tissues, such as the heart, brain, retina and skeletal muscles. Taurine was first …

The skin is a high turnover organ, and its constant renewal depends on the rapid
proliferation of its progenitor cells. The energy requirement for these metabolically active …

The skin is comprised of different cell types with different proliferative capacities. Skin aging
occurs with chronological age and upon exposure to extrinsic factors such as photodamage …

Ageing is the predominant risk factor for many common diseases. Human premature ageing
diseases are powerful model systems to identify and characterize cellular mechanisms that …

Progressive DNA damage and mitochondrial decline are both considered to be prime
instigators of natural ageing. Traditionally, these two pathways have been viewed largely in …

Objective To investigate, using accelerometers, the levels of physical activity being
undertaken by individuals with intellectual disabilities with and without Down's syndrome …

Oxidative stress is a condition determined by an imbalance between antioxidant and
oxidative factors. Oxidative stress can have serious consequences on our organism. Indeed …

Metformin, a biguanide drug, is the most commonly used first-line medication for type 2
diabetes mellites due to its outstanding glucose-lowering ability. After oral administration of …

Autism spectrum disorder (ASD) affects a significant number of individuals worldwide with
the prevalence continuing to grow. It is becoming clear that a large subgroup of individuals …

The process of aging refers to the decay of an organism's structure and function, in which
molecular and cellular modifications can have various effects at the individual level over the …