BACKGROUND: The American Heart Association (AHA), in conjunction with the National
Institutes of Health, annually reports the most up-to-date statistics related to heart disease …

Metformin was first used to treat type 2 diabetes in the late 1950s and in 2022 remains the
first-choice drug used daily by approximately 150 million people. An accumulation of …

Sporadic Parkinson's disease (PD) is a progressive neurodegenerative disease, with a
complex risk structure thought to be influenced by interactions between genetic variants and …

The study of the relationship between type 2 diabetes mellitus (T2DM) disease and other
pathologies (comorbidities), together with patient age variation, poses a challenge for …

This important book provides a broad, integrated overview of current research on word-
finding deficit, anomia, the most common symptom of language dysfunction occurring after …

Alzheimer's disease (AD) constitutes a major public-health issue of our time. Regrettably,
despite our considerable understanding of the pathophysiological aspects of this disease …

Dementia is a growing public health concern, with an estimated prevalence of 57 million
adults worldwide. Alzheimer's disease (AD) accounts for 60–80% of the cases. Clinical trials …

This study aimed to investigate the controversial association between metformin use and
diabetes-associated dementia in elderly patients with type 2 diabetes mellitus (T2DM) and …

Alzheimer's disease (AD) is a global concern and has become a major public health event
affecting human health. Insulin is a metabolic hormone secreted mainly by the peripheral …

Since glucose reuptake by neurons is mostly independent of insulin, it has been an
intriguing question whether insulin has or not any roles in the brain. Consequently, the …